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Zika Virus - ClinicalTrials.gov

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Last Updated: 09 September 2022

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Developmental Outcome After In Utero ZIKV Exposure in Children Without Congenital Zika Syndrome

In 4-12% of cases, Zika-virus infection in pregnancy can cause serious brain damage. Children with significant neurologic injury have a poor developmental outcome, but the developmental outcome of reportedly normal infants following in utero ZIKV-exposure is not well known. The investigators will determine if neurodevelopmental assessment results in children exposed to ZIKV in utero are normal, which differ from norms. The investigators predict that the presence of mild postnatal non-specific cranial U. S. findings is associated with persistent lower developmental outcomes in comparison to ZIKV-exposed children with normal cranial U. S. and quantitative imaging will reveal quantitative and functional brain differences between ZIKV-exposed children and controls. The aim of the study is to determine if children who were exposed to ZIKV in utero and those who do not have CZS have abnormalities in neurogenesis during early childhood and school age.

Source link: https://clinicaltrials.gov/ct2/show/NCT04398901

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions