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Zidovudine - ClinicalTrials.gov

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Last Updated: 08 August 2022

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A Phase III Study With Long-Term Follow-Up of Zidovudine Versus Zidovudine and Alpha-Interferon Versus Alpha-Interferon in Patients With Early HIV Infection

THREE ARM STUDY INTERTERFERON STUDY The first research, conducted in 1988, was the first study to investigate interventions with antiretroviral therapy and alpha interferon in patients with HIV infection. In the first time to first opportunistic infection, lowering HIV viremia, and lessening immune system deterioration in HIV-infected people, it was found that zidovudine vs. IFN. Patients with evidence of HIV infection and a CD4 count greater than or equal to 500 were randomized to one of the three treatment groups. Both alone and in combination with AZT showed that interferon-alpha reduced HIV viral load levels during this pre-HAART study, according to our statistically robust results during this pre-HAART period.

Source link: https://clinicaltrials.gov/ct2/show/NCT01125228

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions