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Both exercise and weight loss are lifestyle choices that can influence glucose metabolism. Both exercise and weight loss are lifestyle habits that can influence glucose metabolism. During a glucose clamp in middle-aged and older adults, the aim of this research was to investigate the effects of a six-month trial of aerobic exercise training or weight loss on signaling pathways in skeletal muscle in the basal condition and during hyperinsulinemia. In the insulin stimulation changes in GSK3 that increased more after WL than AEX, there was a difference between WL and AEX. Changes in M, base total GSK-3 and basal total p70Sk, as well as insulin stimulation of total p70Sk were both associated with changes in the total population's total GSK-3' and basal total p70Sk and basal total p70Sk. Protein signaling in skeletal muscle provides insight into the mechanisms for rises in insulin sensitivity in ageing and obesity.
Source link: https://doi.org/10.3390/cells10123490
According to recent studies, a higher protein diet can prevent lean mass loss in periods of intentional weight gain among older adults with obesity; however, the effects of intentional weight loss on skeletal muscle and bone are not fully understood.
Source link: https://doi.org/10.1080/21551197.2021.1896615
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