Weight Loss - DOAJ

The Effects of High Fiber Rye, Compared to Refined Wheat, on Gut Microbiota Composition, Plasma Short Chain Fatty Acids, and Implications for Weight Loss and Metabolic Risk Factors (the RyeWeight Study)

The effects on body weight and metabolic risk factors may partly be mediated by gut microbiota and/or their fermentation products. We used results from a random controlled weight loss trial in which participants were randomly assigned to a hypocaloric diet containing high fiber rye foods or refined wheat products for a year to investigate the effects of the intervention on intestinal microbiota composition and plasma short chain fatty acids, as well as the potential connection with weight loss and metabolic risk factors. In conclusion, high fiber rye foods caused some changes in gut microbiota composition and plasma short chain fatty acid concentration, which were associated with rises in metabolic risk markers as a result of the intervention.

Source link: https://doi.org/10.3390/nu14081669

Sleep Deprivation: Effects on Weight Loss and Weight Loss Maintenance

This narrative review reviews the findings from intervention studies on the effects of sleep deprivation on eating habits, metabolic rate, and hormones that regulate metabolism, as well as obesity management. The studies focused mostly on the effects of sleep duration, but also on sleep quality, on dietary intake during weight loss trials, and weight loss maintenance.

Source link: https://doi.org/10.3390/nu14081549

Effects of Diet-Induced Weight Loss on Plasma Markers for Cholesterol Absorption and Synthesis: Secondary Analysis of a Randomized Trial in Abdominally Obese Men

Obesity has been shown to lower intestinal cholesterol absorption and increased endogenous cholesterol synthesis in cross-sectional studies, according to cross-sectional studies. The number of intervention studies investigating the impact of weight loss on these metabolic characteristics has been limited, but the role of the different fat compartments has not been investigated in detail. Following weight loss, total cholesterol cholestanol levels increased by 0. 18 mol/mol, while campesterol and lathosterol decreased by 0. 25 mol/mol, respectively, while those of lathosterol and 0. 39 mol/mmol decreased by 0. 25 mol/mol/mol. After weight loss, changes in waist circumference, height, BMI, and visceral fat were all significant, but not with subcutaneous and intrahepatic lipids. In addition, cross-sectional research revealed that visceral fat significantly reduced the connection between BMI and TC-standardized cholestanol levels. The rise in TC-standardized cholestanol levels was not limited to weight loss alone, but also to a decrease in visceral fat volume.

Source link: https://doi.org/10.3390/nu14081546

Rewiring of the Liver Transcriptome across Multiple Time-Scales Is Associated with the Weight Loss-Independent Resolution of NAFLD Following RYGB

To solve this, we've developed a novel graph network-based analysis workflow that helps identify modules enriched with biomolecules that share common dynamic profiles, where the network is constructed from all known biological interactions obtainable through the Kyoto Encyclopedia of Genes and Genomes. In a single review, we found several network modules with statistically significant enhancements of genes whose expression trends mimic acute-phase as well as long-term physiological responses to RYGB. NAFLD and other metabolic syndrome comorbidities can be identified with less sophisticated network modules that may have been skipped with conventional PEA methods, providing a framework for finding novel drug targets for NAFLD and other metabolic syndrome co-morbidities.

Source link: https://doi.org/10.3390/metabo12040318

Weight Loss and Fat Metabolism during Multi-Day High-Altitude Sojourns: A Hypothesis Based on Adipocyte Signaling

Both sexes have lost weight in high-altitude sojourners of both sexes in several journals and random observations. Several journals have discussed the effect on appetite-regulating hormones, which is one of the most common contributing factors. To find relevant studies, we ran a literature search using PubMed according to the PRISMA 2020 protocol. Six articles were included addressing hormonal influences and the effect of exercise on appetite regulation, as well as genetic factors altering metabolic processes at altitude. With an initial rise and a decrease in the course of time at altitude, hunger reduction at altitude appears to be the largest factor to appetite reduction at altitude. A high-fat diet may be beneficial at a certain point in the course of high-altitude sojourns since the utterance of leptin has been linked to an elevated -oxidation of fatty acids.

Source link: https://doi.org/10.3390/life12040545

Endoscopic Intragastric Injection of Botulinum Toxin A in Obese Patients Accelerates Weight Loss after Bariatric Surgery: Follow-Up of a Randomised Controlled Trial (IntraTox Study)

According to previous studies, Intragastric injection of botulinum toxin A has been shown to be safe for weight loss up to six months after administration. Our goal was to find out the effect of BT-A on weight loss in patients on bariatric surgery waiting lists, the effect of BT-A on weight loss in the pre- and postoperative period, as well as determining if body mass index responses differed. Weight loss percentage tended to remain higher in the treatment group one month after the intervention, and became similar three months after.

Source link: https://doi.org/10.3390/jcm11082126

Comparison of Two Diet and Exercise Approaches on Weight Loss and Health Outcomes in Obese Women

Aim: To determine the effectiveness of two common weight loss methods on weight loss, body composition, and health indicators in obese women, sedentary obese women. Methods: In total, 51 sedentary women were matched and selected to enroll in the Weight Watchers ® Momentum ® or Curves ® Fitness and Weight Management program for 16 weeks. Participants in a structured circuit-style resistance training program began with a menu-based higher protein/low-fat diet for a week; 1500 kcal/d diet for three weeks; and 2000–2500 kcals/d for two weeks; and 2000–2500 kcal/d for 2 weeks. Participants in the CV group saw fat mass declines and rises in lean mass, leading to more encouraging changes in percent body fat. Peak aerobic capacity and muscular endurance were both increasing in peak aerobic capacity and muscular endurance, although bench press lifting number was higher in the CV group.

Source link: https://doi.org/10.3390/ijerph19084877

The Association between Rapid Weight Loss and Body Composition in Elite Combat Sports Athletes

Rapid Weight Loss is a drastic drop in weight over a short period of time, trying to reach the required weight class for a competition. RWL has a negative health effect on athletes, especially because of RWL's significant muscle damage. This research was conducted in Lithuania to determine the relationship between RWL and body composition among young competitive combat athletes. About 2% of the normal body mass, 88% of the athletes polled in our report had lost weight in order to compete, with the average weight loss of 4. 6 % of the habitual body mass. During the preparations training phase, RWL magnitude may have played a significant role in retaining muscle mass in athletes. Hence, an appropriate regulatory framework should be embedded into the preparation plans of high-performance combat sports athletes, not only the athletes but also their coaches, who are responsible for effective weight control, should be included.

Source link: https://doi.org/10.3390/healthcare10040665

Prognostic Relevance of Weight and Weight Loss during Multimodal Therapy for Oesophagogastric Tumours

The prognostic meaning of weight loss during routine surgical oesophagogastric cancer therapy is still unclear. Pts with WL 5% during neoadjuvant chemotherapy had remarkably reduced OS after compared to pts with WL > 5% and DFS vs. During the whole course, Pts with WL 14% and DFS 14% had dramatically reduced OS, relative to pts with WL > 14% and DFS 1. 4%. In the context of a multimodal therapy with PC, WL patterns during neoadjuvant chemotherapy and throughout the entire course of therapy correlate with a significantly higher prognosis in operated pts with curative GC or OAC.

Source link: https://doi.org/10.3390/curroncol29040221

Influence of Weight Loss on Cognitive Functions: A Pilot Study of a Multidisciplinary Intervention Program for Obesity Treatment

Under a multidisciplinary weight loss program, our goal was to determine the impact of weight loss on global cognition and executive functioning in adults with obesity. With the Montreal Cognitive Assessment, Neuropsychological Battery of Executive Functions, and Trail Making Test-Part B, an assessment of global cognitive effectiveness was assessed. Patients' cognitive performance improved during the follow-up; however, the severity of weight loss did not correlate with cognitive growth, according to this review. Patients who lose more than 5% of their weight can lead to memory enhancements, in addition to weight loss. Future studies are recommended to determine if patients who experience a 5% weight loss will improve cognition, secondary to weight loss.

Source link: https://doi.org/10.3390/brainsci12040509

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