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Weight Loss - ClinicalTrials.gov

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Last Updated: 24 November 2022

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Pragmatic Weight Loss Intervention During Menopause

Aim 1: Investigate attitudes and perceptions of weight gain during the menopause transition, as well as patient weight loss tips. Aim 2: Engage the Community Advisory Board CAB of the Louisiana Clinical and Translational Center (LAC) to learn the scalability and community-based implementation of an intervention targeted for women in perimenopause. Using findings from the focus groups, the investigators will then use the Louisiana Clinical & Translational Science Center LA CaTS Community Advisory Board CAB to help us design a lifestyle intervention in perimenopausal women.

Source link: https://clinicaltrials.gov/ct2/show/NCT04487782


Optimizing Weight Loss Outcomes Through Body Image Enhancement

Although many comprehensive multidisciplinary weight management programs emphasize behavioral and psychosocial aspects of behavior change, including brief body image analysis, brief body image education, few have concentrated heavily on body image as a potentially influential influence on motivation and/or positive outcomes. The body image is an individual's interpretation of their physical appearance. People with obesity are more likely dissatisfied with their bodies than those without obesity, according to body dissatisfaction, and studies have found that people with obesity are more likely to be dissatisfied with their bodies than those without obesity. body dissatisfaction is a common psychological correlate of obesity. No weight loss programs have attempted to produce a novel body image supplement that specifically addresses the ostensible dichotomy between body acceptance and the desire for body changes in a weight loss program. The investigators will determine if a universally delivered cognitive behavioral lifestyle therapy for weight loss can be enhanced by the incorporation of a novel body image treatment meant to promote body image and height weight loss success.

Source link: https://clinicaltrials.gov/ct2/show/NCT05090293


Pilot Telehealth Weight Loss Program for Breast Cancer Survivors

Participants in Weeks 22 and 24, for a total of 6 months of intervention, will receive weekly group sessions of lifestyle coaching for the first 20 weeks, followed by every other week sessions. Each participant will be sent a digital scale so they can weigh themselves and report their weight to the group's leader each week. Breast Cancer Patient; The International Physical Activity Questionnaire - Breast Cancer Patient - This paper examines the types and intensity of physical fitness and sitting time in which people routinely participate. Acceptability of Intervention Measures According to the Patient Health Questionnaire, investigators will conduct an exit interview with each participant to determine the acceptability of the intervention, the implementation of the technology via telehealth, and the patients' satisfaction with their treatment results. Weight loss among participants will be determined by percentage weight loss to determine body change among participants. Investigators will determine mammographic density changes in mammogram pre- and post weight loss programs in order to determine mammographic breast density changes. Breast cancer survivors are generally scheduled mammograms, except for those who have undergone bilateral mastectomy. The annual mammogram that was performed between 1 month and 12 months prior to weight loss program implementation will be used as baseline pre-intervention. This will be the first annual mammogram performed after the weight loss program, according to the post-intervention mammogram. If regular annual mammogram is administered during the 20-week weight loss initiative, then the following annual mammogram will be used for breast density analysis.

Source link: https://clinicaltrials.gov/ct2/show/NCT04855552


Behavioral Weight Loss Intervention Utilizing Mobile Health Technology in Hematopoietic Stem Cell Transplant Patients

This is a pilot study involving obese patients aged 13 to 30 in an addiction model-based smartphone health weight loss program with coaching at a minimum of 100 days after hematopoietic stem cell transplantation. Participants will participate in two additional in-clinic visits at 2 months and at the end of the study at 4 months following the initial visit. 1 intervene with the participant and provide autonomy over a longer period of time, according to the novel, 3 reduce several key barriers that common in traditional outpatient obesity treatments, such as transportation or missed days of school and work, and 4 support youth in learning how to cope with their addictive eating habits. The current model of delivery makes it possible to: 1 interfere with the participant and provide independence, while 2 release the information over a longer period of time, as well as transportation or missing days of school and work.

Source link: https://clinicaltrials.gov/ct2/show/NCT04997473


To Predict Weight Loss Response to Liraglutide (Saxenda®), From fMRI-based Determination of Food Cue Reactivity

Following baseline findings, subjects will be randomly assigned to either Saxendae or placebo group. The aim of the investigation is to determine contributing factors contributing to early weight loss in a Saxenda'u00ae health care service. The current studies will determine whether Saxendau00ae improves brain function by altering in behavioral and physiological parameters, allowing the researchers to determine whether or not the change is due to changes in behavioral and physiological variables.

Source link: https://clinicaltrials.gov/ct2/show/NCT03795701


Effects of a Weight Loss Program in People With Hip Osteoarthritis: a Randomised Controlled Trial

Exercise is the primary therapy for symptoms, according to clinical guidelines, but hip OA results contradict contradicting findings regarding weight loss for people with hip OA. Weight loss is commonly associated with overweight or obese people, but it's unclear if weight loss in conjunction with exercise and regular physical activity is superior to exercise alone for hip OA symptoms. This study is a random controlled trial in which the aim is to determine whether a weight loss and exercise program improves hip pain more than an exercise program alone at 6 months among people with hip OA who have overweight or obese. Any participant will be randomly assigned to either a weight loss plus exercise program or a b exercise program alone, over 6 months. Participants in the exercise plus weight loss study will be randomly assigned to one of the exercise group's physiotherapists as the exercise group and a dietitian. Participants in both groups will receive 5 individual physiotherapy consultations via video-conference over 6 months and will begin a home-based lower limb muscle strengthening exercise and physical fitness program. Many in the weight loss and exercise group will also try a ketogenic very low calorie diet VLCD, which has been shown to be a safe and effective way of losing weight in the adult population of overweight/obesity.

Source link: https://clinicaltrials.gov/ct2/show/NCT04825483


Apollo OverStitch for Bariatric Surgery Revision After Weight Loss Failure

Both roux-en-Y gastric bypass and sleeve gastrectomy are commonly performed laparoscopically in the United States, and the majority are both roux-en-Y gastric bypass and sleeve gastrectomy. It is hypothesized that the RYGB's weight loss is due to gastrojejunostomy dilation, which is defined as > 2 cm. The investigators plan to use Apollo EndoSurgery's endoscopic suturing device to minimize the GJ dilation to 5-6 mm, resulting in restriction, delayed food transit time, and early satiety. Patients with previous SG may have a dilation of their stomach, according to reports. The investigators develop a pyloric cerclage using the Apollo EndoSurgery suturing device by closing the door of the pylorus pylorus, thus achieving the same objectives as the investigators did above with the RYGB's revision, which coincides with the same objectives as the investigators set above. Endoscopic procedures are same day surgeries with little morbidity and mortality when compared to laparoscopic or open bariatric surgery revisions.

Source link: https://clinicaltrials.gov/ct2/show/NCT01871896


Optimization of a mHealth Behavioral Weight Loss Intervention for Young Adults

"Just-in-Time Adaptive Interventions" - a series of evolving digital intervention methods that promise to improve on outcomes by giving real-time, personalized feedback on behavior rather than on a preset schedule. The emergence of low-cost, widely available digital health products that enable for the collection of continuously updated health information is made possible by the emergence of low-cost, "just-in-time" or JIT techniques that make it possible. Nevertheless, only a few studies have used JIT techniques in remotely delivered, fully scalable weight loss interventions. participants will be tested to standardized vs. adaptive, 2 key decision factors for message content standard vs. adaptive, and 5 message choice no vs. yes. With the intention of determining whether greater adaptation will lead to increased weight loss, participants will be randomized to improved vs. enhanced, 2 health promotion goals weekly vs. daily, 1 health monitoring approach standard vs. customizable, 3 decision points for message content standard vs. responsive, and 5 decision points for message content standard vs. 1 Build an optimized JITAI consisting of the following objectives: 1 Design and implement empirical research of program engagement; and 2 Conduct exploratory studies of program engagement; and 3 Conduct initial research and reporting of program involvement.

Source link: https://clinicaltrials.gov/ct2/show/NCT04922216


Gastric Fundus Ablation Plus Endoscopic Sleeve Gastroplasty for Weight Loss

To produce a restricted, sleeve gastroplasty type, the endoscopic sleeve gastroplasty employs full-thickness suturing to imbricate the stomach along the greater curvature. Although the ESG recapitulates the design of a gastric sleeve, it has yet to achieve as positive weight loss results as compared to laparoscopic sleeve gastrectomy. The former does not include the gastric fundus, which is a major difference between ESG and LSG. Following LSG, studies have shown reduced ghrelin levels at various time points, which has been attributed to the fundus' targeting, as bariatric surgeries that did not involve the fundus did not show a decrease in circulating plasma ghrelin. In comparison, patients who had undergone ESG and LSG did not show any decrease in fasting ghrelin levels, 8 ostensibly due to fundic-sparing.

Source link: https://clinicaltrials.gov/ct2/show/NCT05578703

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions