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Vitamin D - DOAJ

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Last Updated: 22 June 2022

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Study of association of serum vitamin D and serum calcium with spontaneous aneurysmal subarachnoid haemorrhage in a tertiary care centre

Vitamin D deficiency and aSAH have been linked to a correlation, according to recent studies, but the exact mechanism of which is unclear. Vitamin D and Calcium in patients with aSAH have not been investigated informally. In patients with aSAH, hypovitaminosis D and hypocalcemia were discovered in this research. During the period from January 2019 to April 2020, 40 patients with spontaneous aneurysmal SAH were enrolled from January 2019 to 20th. Results: The study found mean vitamin D level of 17. 4 ng/ml amongst the study participants; mean calcium level of 8. 3 u00b1 0. 9 mg/dl. Out of 40 patients, 8 patients were severely impaired, 24 patients were mild to moderately obese, and 8 patients were having normal vitamin D levels. Conclusion: In our study, a higher risk of vitamin D deficiency was found in our study, as well as an equal incidence of hypocalcemia versus normocalcemia.

Source link: https://doaj.org/article/c6404afbe8c043c2b1aa9d08a2caa314


Corrective osteotomy for complex tibial deformity in a patient with hereditary vitamin D-resistant hypophosphatemic rickets (HVDRR) using CT-based navigation system and 3D printed osteotomy model

However, one disadvantage of using navigation devices is that osteotomies are performed on tracker-attached bone; however, bone fragments on the side where osteotomies were taken cannot be traced. In an adult man, we used these methods to perform segmental corrective osteotomy for a complex tibial deformity with intramedullary nail fixation case of hereditary vitamin D-resistant hypophosphatemic rickets. To shield the thin and stretched skin around the deformed tibia, we decided to use an IMN for correction and fixation of tibial deformity. In addition, we may be able to ensure accurate preparation of a closed medullary canal for the IMN placement by referring to the 3D printed bone models. The bone union at the osteotomy sites was confirmed six months after the surgery, and the patient was able to return to his normal life and work.

Source link: https://doi.org/10.1080/24699322.2022.2086485


Comparative assessment of cognitive impairment and oxidative stress markers among vitamin D insufficient elderly patients with and without type 2 diabetes mellitus (T2DM)

Background disorders of mental stability are known to influence cognitive functions, which are hence termed cognitive disorders. Type-2 diabetes mellitus is one of the reported contributing factors of cognitive decline and dementia. Methods A cross sectional research was conducted in 145 subjects who were tested for cognitive function by a modified mini mental status examination. 35 diabetics with vitamin D insufficiency had cognitive impairment, 35 patients had cognitive impairment, but 27 subjects with vitamin D insufficiency had cognitive impairment. There was no significant correlation between diabetes, vitamin D deficiency, and cognitive impairment in the Chi square study, according to the Chi square questionnaire. When compared to cognition normal diabetics with vitamin D insufficiency, glucose, and superoxide dismutase were non-significantly lower in cognition-impaired participants. Conclusion of the study found that cognitive impairment is more prevalent in diabetics. Inadequate non-diabetics, a significant association was only identified with GPx and 3MSE in vitamin D.

Source link: https://doaj.org/article/061bedc7e54f4112838f9addd2612677


Histopathological role of vitamin D deficiency in recurrent/chronic tonsillitis pathogenesis: Vascular epithelial growth factor‐mediated angiogenesis in tonsil

Abstract Objectives The aim of this report is to reveal the role of vitamin D deficiency in the pathogenesis of recurrent/chronic tonsillitis in the pathogenesis of recurrent/chronic tonsillitis in this disease's pathogenesis, as well as the expression of vascular epithelial growth factor. As Group 1, 11, 11u201320 ng/ml Group 3, with 31u201350 ng/ml control Group 4 confirmed patients with 25OHD values 0/ml and 31u201350 ng/ml Group 3, with 25OHD levels 0–u201310 ng/ml Group 3, 2011-20 ng/ml Group 3, and 31u201350 ng/ml Group 4, with 25OHD values 0+u201310 u201330 mg/ml Group 2, 11/ml Group 2, 21 u201330 ml Group 3, 201350 eng/ml Group 2, 21/ml Group 4, 201350 ng/ml Group 1, 11 ng/ml Group 4, 201320 ng/ml Group 4, and 31/ml Group 2, 21 ng/ml Group 4, and 31–u201320 ng/ml Group 2, 11 ng/ml Group 4, and 31u201350 mg/ml Group 4, with 25OHD ng/ml Group 3, 21 ng/ml Group 3, and 31/ml Group 2, 1 For each group, immunohistochemically tested VEGF expression was determined immunohistochemically. Result The results of our investigation revealed VEGF expression in both study groups. Histopathological results in Group 1 and Group 2 were both significantly higher than those in other groups. The patients in Groups 1 and 2 with high VEGF levels were significantly lower than those in other groups, with significant VEGF expressions in both Groups 1 and 2 being significantly lower than those in other groups. Conclusions and Conclusions This research found an increased angiogenesis in tonsil and a rise in VEGF expression of the tonsillar surface epithelium in blood serum 25OHD levels 20 ng/ml.

Source link: https://doi.org/10.1002/cre2.539


Study of association of serum vitamin D and serum calcium with spontaneous aneurysmal subarachnoid haemorrhage in a tertiary care centre

Vitamin D deficiency and aSAH have been linked to a correlation, according to new studies, but the exact mechanism of which is unknown. Vitamin D and Calcium in patients with aSAH have not been investigated informally. Hypovitaminosis D and hypocalcemia in patients with a SAH were also determined by this analysis. During the period January 2019 to April 2020, 40 patients with spontaneous aneurysmal SAH were enrolled from January 2019 to April 2020. parab1 0. 9 mg/dl among study participants, resulting in a mean vitamin D level of 17. 4 ng/ml. Out of 40 patients, 8 patients were severely inadequate, 24 patients were mild to moderately ill, and 8 patients were having normal vitamin D levels. Conclusion: In our study, vitamin D deficiency was linked to a higher risk of vitamin D deficiency, as well as an equal number of hypocalcemia versus normocalcemia.

Source link: https://doaj.org/article/b9cff0e186774e25978aea05d217fab8


Vitamin D Deficiency among Patients Presenting to Outpatient Department of Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study

Introduction: Vitamin D deficiency is a global health issue, with over billions of people worldwide suffering from vitamin D deficiency or insufficient. This report was designed to find out the prevalence of vitamin D deficiency in patients attending to a hospital outpatient Department of Medicine of a tertiary care center. In 215 patients, vitamin D deficiency was found out of 362 patients. Conclusions: Vitamin D deficiency prevalence was found to be lower than other studies conducted in similar settings.

Source link: https://doi.org/10.31729/jnma.7452


Vitamin D Deficiency and Its Response to Supplementation as “Stoss Therapy” in Children with Cyanotic Congenital Heart Disease Undergoing Open Heart Surgery

Patients with congenital heart disease have been vitamin D deficient, according to several studies. Objects We wanted to investigate the prevalence of vitD deficiency pre and post cardiac surgery as well as the effects of vitD supplementation on postoperative convalescence of the children with tetralogy of Fallot undergoing intracardiac repair, but not the children with tetralogy of Fallot. Methodology 60 children younger than 18 years with TOF and serum vitD levels 20ng/dL were randomly divided into two groups in this randomized controlled trial. When compared to the control group, the study group found higher serum vitD levels in the immediate preoperative period, postoperative period after CPB, and on the first postoperative day. Children with TOF are severely deficient in vitD, their level drops further after CPB, and supplementing vitD preoperatively does not have a direct effect on postoperative recovery patterns.

Source link: https://doi.org/10.1055/s-0039-1696910


Depression and its Association with Vitamin D Deficiency: A Review

The connection between vitamin D and depression has been extensively investigated in recent years; yet, the system that controls this association is still not fully understood. Vitamin D's involvement in determining the underlying biological pathways and mechanisms by which vitamin D actss its role can aid in diagnosing depression and the occurrence of depression.

Source link: https://doi.org/10.32350/BSR.0204.04


Association of Vitamin D Anabolism-Related Gene Polymorphisms and Susceptibility to Uterine Leiomyomas

Vitamin D deficiency in patients with ULs was confirmed in our previous research. paraphrasedoutput:Methods: The association of vitamin D anabolism-related gene polymorphisms in 110 patients with ULs and 110 healthy controls was unclear, but the 92 SNP differences were determined in both groups by chi-square test. The DHCR7 rs1044482 polymorphisms were correlated with ULs risks in women over 40 and with 18. 5-u201325. 0 BMI, according to a stratified review. The correlation between NADSYN1 rs2276360 and ULs risk was not clear in contrast to the wild-type CG haplotype vectors, especially in patients over 40 with 18. 5 b. a 201325. 0 BMI, although ULs were still at a higher risk of developing ULs.

Source link: https://doi.org/10.3389/fgene.2022.844684


The association of vitamin D, semen parameters, and reproductive hormones with male infertility: A cross-sectional study

Abstract Background: Vitamin D deficiency and male infertility in Iran are common. Subjects were divided into three groups based on serum vitamin D levels: deficient, insufficient, and sufficient. Also, serum LH and estradiol were significantly lower in the appropriate group, and serum sex hormone binding globulin and the testosterone/LH ratio were both elevated in comparison to the ineffective and deficient groups. In Iranian infertile males, our study found a positive correlation between serum vitamin D levels, seminal measurements, and sex hormones.

Source link: https://doi.org/10.18502/ijrm.v20i4.10905

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions