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Vitamin C being one of the key quality indicators, as a result of the regular demand for healthy and high-quality food has led to the need for improved ways to analyze food composition. This review focuses on the main findings on the testing of vitamin C in foods using vibrational spectroscopic techniques. According to qualitative characterization and quantitative analysis, the use and importance of vibrational spectroscopy in the evaluation of vitamin C is shown.
Source link: https://doi.org/10.1007/s00217-022-04023-w
Atrazine is one of Brazil's most commonly used pesticides; several research have reported the toxic effects of this herbicide on aquatic organisms such as fish. In Rhamdia quelen fish exposed to this herbicide, the goal of the current research was to investigate correlations between vitamin C antioxidant supplementation and exposure to ATZ. The R. quelen specimens were divided into four groups: CTRL, VitC, ATZ, ATZ + VitC. Group 4 was the only group to sell reduced protein carbonyl levels. In group VitC and lower in group ATZ, Ascorbic acid levels were noticeably higher than in group VitC and lower in group ATZ. According to a result, biochemical interactions between herbicide ATZ and dietary supplementation with Vit C have resulted in biochemical changes in R. quelen fish. Hence, nutritional supplements with adequate amounts of Vit C can be added as antioxidants to fish bred in aquaculture systems in order to shield them from ATZ exposure.
Source link: https://doi.org/10.1007/s00244-022-00926-7
The effectiveness of combined therapy of vitamins A and C on experimental autoimmune encephalomyelitis and myelin repair mechanisms was investigated in this review. Following co-administration of vitamins A and C, a significant decrease in denyelination, inflammation, and immune cell infiltration, as well as microglia and astrocyte activation were found by a histological study. Vitamin A and C supplementation therapy also improved the total antioxidant capacity and reduced the number of oxidative stress markers, as well as decreased amounts of oxidative stress markers. According to the present research, combined vitamin A and C supplementation may be a safe option for developing alternative medicine in improving myelin repair in demyelinating diseases.
Source link: https://doi.org/10.1007/s12035-022-02755-0
Background: Vitamin C infusion has been used to treat critically ill patients, including pneumonia- and severe COVID-19. In a recent genome-wide association study as genetic tools to the GWAS of severe COVID-19, COVID-19 hospitalization, and pneumonia in the UK Biobank, we tested whether people with genetically predicted higher plasma vitamin C had a reduced risk of severe COVID-19 and pneumonia. Conclusions Mendelian randomization analysis showed no evidence for a correlation of genetically predicted circulating vitamin C with COVID-19 or pneumonia, and thus our results are no support for vitamin C's use in prevention and treatment in these patients, but no evidence has been provided for the use of vitamin C in prevention and therapy, since high dose vitamin C infusion has therapeutic effects via different biological pathways.
Source link: https://doi.org/10.1038/s41430-021-00993-4
The switch from the garbages to lithium-ion batteries' electrode materials is essential for long-term development. In this work, LiFePO_4/C was extracted from two wastes, and the beneficial function of vitamin C was also investigated. LFP/C cathode capacity at 1. 0 C for 400 cycles was 134. 6 mAhg1 at 1. 0 C for 400 cycles, up more than 123. 2 mAh/g1 capacity.
Source link: https://doi.org/10.1007/s11581-021-04405-2
Three groups of 24 animals were developed to see if there was any effect of QP on the rat ileum, which could be rectified by using Vit C. For ten days, Third group rats were given oral gavages of Vit C plus QPs. Normal goblet cells were also observed in this absorptive columnar cell, which contained several vacuoles inside, as well as herniation of microvilli. Many Paneth cells into the lumen of intestinal gland's lumen were found to contain mystery granules of various sizes and shapes. The histological structure of the ileal mucosa in the QP+ Vit C group was discovered to be close to those of healthy controls. According to the results of this report, administering Vit C in rats treated with QPs shields them from ill dysfunction caused by QP.
Source link: https://doi.org/10.1007/s11356-022-19820-9
Vitamin C has been shown as a cure for acute sepsis and acute respiratory distress syndrome in severe COVID-19 studies; however, there are no studies examining its use in severe COVID-19. In patients with severe COVID-19, the effectiveness and safety of high-dose IV-VitC were determined. To compare outcomes in patients with severe COVID-19 treated with and without HDIVC, Inverse probability treatment weighting was used. Patients with HDIVC died by an average of 22. 9 days compared to 13. 7 days for control patients. Patients with HDIVC had significantly lower rates of mechanical ventilation and cardiac arrest than those who did not. HDIVC may be a safe and effective therapy in lowering the incidences of mechanical ventilation and cardiac arrest in hospitalized patients with severe COVID-19. HDIVC may prevent clinical decline in severe COVID-19 patients who have a longer hospital stay and a longer time to death, suggesting that HDIVC can shield against clinical deterioration. 19.
Source link: https://doi.org/10.1007/s11739-022-02954-6
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