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Methods With prospective results from a community-based research in young Black women, we investigated baseline BV relationships with fibroid incidence and growth. Using Cox proportional hazards models among 1027 women fibroid-free at baseline, we calculated adjusted hazard ratios and 95% confidence intervals for incidence comparing BV and no BV in comparison to no BV and no BV. Conclusions There were n = 247 incident fibroids and 1181 growth plans; average fibroid growth in 18 months was a 78% increase in volume. BV prevalence was 51% and not associated with fibroid incidence or expansion, with no difference in growth, -3%. Conclusions and Conclusions In this first review of ultrasound-monitored fibroid formation and Nugent-assessed BV, we found no evidence to back up the assertion that BV raised the risk of fibroids in Black women's high prevalence of fibroids.
Source link: https://europepmc.org/article/MED/35067565
Purpose: Objectives: To determine the accuracy of information published in YouTube videos on the treatment of uterine fibroids. paraphrased embolization of uterine fibroid embolization. The DISCERN Scale Criterion was used to determine the quality of YouTube videos on uterine fibroid embolization. paraphrased embolization in uterine fibroid embolization. The Video Power Index was used to determine the success of videos on uterine fibroid embolization. A substantially lower Video Power Index for a board-certified interventional radiologist had a significantly lower Video Power Index than those without a board-certified practitioner. Conclusion YouTube is not currently a high-quality resource of information for uterine fibroid therapy options.
Source link: https://europepmc.org/article/MED/35487248
Cadmium is one of the most common environmental heavy metal contaminants and has been described as an endocrine disruptor and carcinogen. Blood Cd levels are linked to fibroid tumor size in women with uterine fibroids. We performed time lapse imaging using a Zeiss confocal microscope and analyzed results by Imaris and RStudio to determine the morphological and mechanodynamic characteristics of uterine fibroid cells resulting from prolonged Cd exposure. More than 64,000 trackable nuclear surface objects were found in our experiments, with each having multiple parameters such as nuclear size and shape, speed, location, orientation, track length, and straightness. According to a quantitative report, prolonged Cd exposure significantly changed cell migration behavior, such as longer track length and reduced track straightness. The direction of gene expression changes as a result of Cd exposure enhanced cell migration and invasion, according to NanoString analysis and Ingenuity Pathway Analysis.
Source link: https://europepmc.org/article/MED/35453667
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