Advanced searches left 3/3

Uterine fibroid - ClinicalTrials.gov

Summarized by Plex Scholar
Last Updated: 07 May 2022

* If you want to update the article please login/register

Is There a Place for Pre-operative Temporary Embolization of Uterine Fibroids

Uterine fibroids are the most common benign tumors of the female genital tract, with an estimated prevalence of 25-80% during the reproductive period in the general population. If the affected patients do not have any symptoms, uterine fibroids may also be responsible for acute and chronic pelvic pain, bleeding, and infertility, depending on their location. paraphrase fibroids that are characteristic uterine fibroids are now being treated in the first line by surgery. Myomectomy can be performed by laparotomy or laparoscopy when conservative treatment is indicated and the fibroid is not hysteroscopically accessible. The surgeon and the patient are then exposed to a risk of bleeding per- and/or postoperatively, often vascularized, resulting in an increase in operating times, an elevated risk of postoperative complications, and the need for transplantation. For several years in the treatment of fibroids, whether alone or in combination with surgical myomectomy, the effectiveness of uterine artery embolization has been demonstrated. Preoperative embolization studies have published promising findings, including the need for per or post-operative transfusion, the need for surgical reconstruction, or even the decision to hystérectomie. Hypo-infusion failure could be attributed to embolization of the uterine arteries using non-absorbable material, according to various studies. This retrospective case-control study seeks to compare the occurrence of per-and post-operative adverse outcomes in a test group of patients who had undergone preoperative embolization prior to myomectomy, and a control group with myomectomy without embolization.

Source link: https://clinicaltrials.gov/ct2/show/NCT03989661


Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea (FRIEND)

The aim of this research is to perform a controlled double-blinded clinical trial to find the effect of low caffeine green tea extract on fibroids and subsequent pregnancy in women seeking fertility therapy. The investigators hypothesize that EGCG in low caffeine green tea extract will reduce the fibroid size, improve the quality of endometrium, and increase the risk of pregnancy. For up to seven months, participants will be randomized to either oral low caffeine green tea extract vs. placebo for up to 7 months, with a 3-month trial followed by ovarian stimulation with clomiphene citrate and timed intrauterine insemination for up to three cycles.

Source link: https://clinicaltrials.gov/ct2/show/NCT05364008


Comparison of Pain After Uterine Artery Embolization Using Gelatin Microsphere or Tris-acryl Gelatin Microsphere in Patients With Symptomatic Fibroids: A Prospective, Randomized Study

In patients with symptomatic fibroids, this investigation is intended to compare pain after uterine artery embolization using Gelatin microsphere or tris-acryl microsphere. The primary end-points will be evaluated by determining the highest Visual Analogue Scale score for each time points within 24 hours after embolization. Patients between the ages of 20 and 60 years old were diagnosed with uterine myoma and plan to perform uterine artery embolization.

Source link: https://clinicaltrials.gov/ct2/show/NCT05086770

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions