Advanced searches left 3/3

Type 2 Diabetes - DOAJ

Summarized by Plex Scholar
Last Updated: 09 November 2022

* If you want to update the article please login/register

Sleep Quality and Its Determinants Among Type 2 Diabetes Patients with Comorbid Metabolic Syndrome

Poor sleep quality in diabetic patients was higher than in the general population. Using SPSS Version 28, the prevalence of poor sleep quality in T2DM with comorbid MS patients was 59%. Age, which was positively related to short sleep quality, was found in this report, which was also poor quality of life and increasing age were all associated with poor sleep quality. Conclusion: This report found that depression, anxiety, poor quality of life, and increasing age were all associated with short sleep quality. The increasing age was linked to short sleep duration and low sleep quality, sleep latency, sleep duration, and sleep quality, among other factors.

Source link: https://doaj.org/article/0494e91e0576406a82333a061bf9bdc9


Eugenol improves high-fat diet/streptomycin-induced type 2 diabetes mellitus (T2DM) mice muscle dysfunction by alleviating inflammation and increasing muscle glucose uptake

However, the protective effect of eugenol on diabetes muscle function is uncertain. In a mouse model, a high-fat diet as a result of a streptozocin injection triggered type II diabetes mellitus. Eugenol reduced HFD/STZ-induced muscle inflammation and muscle atrophy, as well as muscle weakness and atrophy. In conclusion, eugenol is a promising nutraceutical for preventing high-glucose-induced muscle wasting, which could be explained by its mediating effects on glucose absorption and inflammatory responses in the muscle.

Source link: https://doi.org/10.3389/fnut.2022.1039753


Short-term Heart Rate Variability to Evaluate Cardiovascular Autonomic Neuropathy in Newly Diagnosed Type 2 Diabetes Mellitus Patients: A Cross-sectional Study

Type 2 Diabetes Mellitus patients can be seen with cardiovascular autonomic neuropathy, according to a press. In several previous studies, it was found that there is reduced heart rate variability among DM patients. The findings of a short-term Heart Rate Variability analysis of five minutes were similar to standard 24 hours HRV analysis, according to various earlier studies. CAN is generally linked to a longer duration of illness, but according to some studies, it is also present in newly diagnosed diabetic diabetes patients, but the percentage is lower. Aim: To assess the short-term HRV profile as cardiovascular risks among newly diagnosed T2DM patients and to determine the relationship between HRV parameters with disease duration and biochemical parameters, see Fasting Plasma Glucose and Postprandial Plasma Glucose for early detection and management of CAN. The study participants were divided by the Standard deviation of NN intervals as a cardiovascular risk factor. Group 1 was the low risk group, group 2 was the moderate risk group, and Group 3 was the high-risk group. The present study found a significantly higher LF/HF ratio in males than in females by assessing HRV parameters as cardiovascular risk factors among newly diagnosed T2DM patients. The SDNN value was both significantly higher in a low cardiovascular risk group and the lowest in a high cardiovascular risk group. Conclusion: The present review found that cardiac autonomic neuropathy is present even at the time of diagnosis of newly diagnosed T2DM, despite a sympathovagal imbalance.

Source link: https://doi.org/10.7860/JCDR/2022/54981.16963


Dyslipidemia among patients with type 2 diabetes in Jordan: Prevalence, pattern, and associated factors

Methods A cross-sectional study was conducted at the National Center for Diabetes, Endocrinology, and Genetics in Amman, Jordan. The aim of this study was to determine the prevalence and patterns of dyslipidemia and its associated risk factors in patients with type 2 diabetes at the National Center for Diabetes, Endocrinology, and Genetics. During the period September-2021, a total of 971 patients with type 2 diabetes were diagnosed between September and December 2021. Results The last three studies on lipid profile and HbA1C were abstracted from medical studies. The overall prevalence of dyslipidemia among type 2 diabetic patients was 95 percent. The most common form of dyslipidemia was combined dyslipidemia, with high triglycerides and low HDL-c being the most common form. In addition, smoking and poor compliance with statin therapy were both correlated with elevated LDL-c levels. Low HDL-c level in patients with type 2 diabetes was found in patients with type 2 diabetes, according to the author's summary.

Source link: https://doi.org/10.3389/fpubh.2022.1002466


Relationship between serum indirect bilirubin levels and skeletal muscle mass in older male and female patients with type 2 diabetes.

The aim of this research is to determine the connection between serum bilirubin levels and skeletal muscle mass in elderly patients with type2 diabetes. Methods For Patients With Type 2 Diabetes, 60 years and over, were steadily recruited from April 2020 to July 2020. As appendicular muscle mass divided by height squared, the skeletal muscle mass index was calculated. In both male and female, the SMI was markedly lower in old-old patients than in young-old patients. The SMI was linked to body mass index and age in male young-old patients, according to a multivariate regression study, although it was associated with BMI, age, and serum indirect bilirubin levels in male elderly patients. Conclusions: The reduced skeletal muscle mass in male older patients with type 2 diabetes may be related to decreased skeletal muscle mass in male older patients with type 2 diabetes.

Source link: https://doi.org/10.1371/journal.pone.0276976


The predictive value of trunk/leg fat ratio for type 2 diabetes mellitus remission after bariatric surgery: A new observation and insight

paraphrasedoutput:MethodsObjective study: In this retrospective observational study, 72 patients with T2DM who underwent bariatric surgery in our center between September 2010 and December 2018 were included. Objectives: This review sought to determine the predictive value of representative parameters of body composition and fat distribution for T2DM remission after bariatric surgery. MethodsOver, T2DM remission after bariatric surgery. MethodsBackground In this retrospective observational Patients in the remission group had elevated body fat percentage and a lower trunk/leg fat ratio than those in the non-remission group. Compared to BMI and body fat percentage, the area under receiver operating characteristic curve for predicting T2DM remission was higher for trunk/leg fat ratios than for body fat percentage. The BMI/BMI relationship between trunk/leg fat ratio and BMI is a promising predictor of T2DM remission following bariatric surgery.

Source link: https://doi.org/10.3389/fendo.2022.1068917


Association of metabolic dysfunction-associated fatty liver disease, type 2 diabetes mellitus, and metabolic goal achievement with risk of chronic kidney disease

paraphrasedoutput:Methods In this cross-sectional study, 5,594 people were included, and we wanted to investigate the correlation between MAFLD, T2DM, and the risk of CKD. ResultsThe MAFLD group had a higher rate of CKD, metabolic goal achievement, and risk of CKD, as well as eGFR and UACR were all used to investigate the correlation between MAFLD and metabolic goal achievement and risk of CKD, as well as UACR and UACR. Glycemic deterioration in MAFLD was dose-dependently linked to an elevated risk of CKD. Glucolytic deterioration in MAFLD was dose-dependently correlated with an elevated risk of CKD. Achieving dietary goals in MAFLD reduced the risk of CKD by lowering the risk of albuminuria.

Source link: https://doi.org/10.3389/fpubh.2022.1047794


Individual and combined effects of the GSTM1, GSTT1, and GSTP1 polymorphisms on type 2 diabetes mellitus risk: A systematic review and meta-analysis

GSTT1 gene polymorphism significantly raises the risk of T2DM complications, according to T2DM complications, while GSTM1 and GSTP1 polymorphisms had no statistical significance. The GSTM1 null genotype had been attributed to a significantly elevated risk of T2DM in Caucasians; the GSTT1 null genotype was linked to a significantly elevated risk of T2DM in Asians and Indians; and the GSTM1 null genotype was correlated to a substantial T2DM risk in Indians. Moreover, the GSTM1 and GSTT1 double null genotype, as well as elevated T2DM risk in Caucasians and Indians, was linked to elevated T2DM risk in Caucasians and Indians; however, the combined effect of GSTM1 and GSTP1 polymorphisms was associated with elevated T2DM risk in Caucasians and Indians.

Source link: https://doi.org/10.3389/fgene.2022.959291


Waist-to-height ratio is a simple and practical alternative to waist circumference to diagnose metabolic syndrome in type 2 diabetes

According to WC and WHtR, MetS prevalence was 79. 4% in women and 68. 6% in male T2DM patients, which was very close to the prevalence of MetS in both women and men, according to WC and WHtR. Result: According to WC and WHtR, the consistency of two diagnostic methods for MetS was determined by Kappa tests, which was very close to the prevalence of MetS in both women and men. After adjustment for age and duration of diabetes, the prevalence of MetS diagnosed by WC in both men and women with WHtR 0. 52 was much higher than in those with WHtR 0. 52. Conclusion: The WHtR test in T2DM patients showed that there was a high degree of agreement between the diagnosis of MetS based on WC and TWTR, which can be used as a simple and inexpensive alternative to WC in T2DM patients, regardless of gender.

Source link: https://doi.org/10.3389/fnut.2022.986090


Monocyte to high-density lipoprotein and apolipoprotein A1 ratios are associated with bone homeostasis imbalance caused by chronic inflammation in postmenopausal women with type 2 diabetes mellitus

Objective: Chronic inflammation has been shown to influence bone metabolism in type 2 diabetes mellitus, contributing to bone homeostasis imbalance, according to new findings. paraphrasedoutput:Method: A total of 619 people with complete data were included in the final analysis, with a total of 619 participants with complete data included. The aim of this study was to determine correlations between novel pro-inflammatory indices such as monocyte to high-density lipoprotein, apolipoprotein A1 ratios, bone mineral density, bone turnover markers in Chinese postmenopausal women with T2DM. Method: This study was designed to Results: The prevalence of osteoporosis in MHR and MAR was 38. 3%, according to the results. MHR and MAR were both well-off values, with 4. 53 mmol and 4. 74 108/g respectively. Conclusion: Osterosis was strongly linked to MHR and MAR's optimal cut-off values of 4. 53 108/mmol and 4. 74 % respectively. These two new pro-inflammatory indices may be helpful in detecting bone homeostasis imbalance in Chinese postmenopausal women with T2DM.

Source link: https://doi.org/10.3389/fphar.2022.1062999

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions