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Treatment Trial - PubMed

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Last Updated: 06 July 2022

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Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial.

According to research, inflammation is a key mediator in anxiety disorders' pathophysiology. In addition, women are more likely to experience an anxiety and depression disorder in comorbidity with a wide range of illnesses related to the immune system. In a sample of women with panic disorder, the present research seeks to investigate the effects of psychological treatment and a hydrogen-rich drink on anxiety and depression, pro-inflammatory cytokine levels, the cortisol awakening reaction, and general health status in a sample of women with panic disorder. Compared to the control group that received psychological therapy and placebo, the treatment group simultaneously received psychological counseling and 1. 5 L of hydrogenated water for three months. When between-group treatment effects were removed, psychological therapy greatly reduced measured variables, such as cytokines and cortisol, which included cytokines and cortisol, when between-group treatment effects were eliminated, including cytokines and cortisol. The findings point to the existence of a maladaptive inflammatory process in women with panic disorder.

Source link: https://doi.org/10.52965/001c.35468


Economic evaluation of day hospital versus intensive outpatient mentalization-based treatment alongside a randomized controlled trial with 36-month follow-up.

Both day-hospital and intensive outpatient MBT services have shown a good success in the treatment of borderline personality disorder. MBT-DH versus MBT-IOP was a health economic analysis conducted by a multicenter random controlled trial with a 36-month follow-up. 114 patients were randomly assigned to MBT-DH or MBT-IOP and monitored every 6 months in three mental health-care centers in the Netherlands. u20ac107,000. One additional QALY with MBT-DH was added to the overall cost for one additional QALY with MBT-DH relative to MBT-IOP. Assuming a willingness-to-pay threshold of u20ac50,000 for a QALY, there is a 33% likelihood that MBT-DH is more cost-effective than MBT-IOP in terms of costs per QAly, according to a QALY. Although MBT-DH results in marginally more QALYs and remission months, it is not cost-effective when compared to MBT-IOP for BPD patients, because the minor additional health benefits in MBT-DH did not outweigh the substantial social costs, which did not justify the substantial higher societal costs.

Source link: https://doi.org/10.1037/per0000577


Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19).

Resveratrol is a polyphenol that has been well researched and has shown anti-viral and anti-inflammatory properties, which may help to reduce the effects of COVID-19. Both groups received a single dose of Vitamin D3 that was used as an adjunct. Hospitalization within 21 days of disease onset was the primary outcome measure; secondary outcomes were ER visits, incidence of pneumonia, and the incidence of pulmonary embolism. In this phase 2 research treated with resveratrol, hospitalization, COVID-19-related ER visits, and pneumonia, the outpatients were at a reduced risk compared to placebo. One patient in each group experienced respiratory embolism pulmonary embolism.

Source link: https://doi.org/10.1038/s41598-022-13920-9

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions