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Townes-Brocks syndrome is a genetic disorder that affects multiple areas of the body. Other signs and symptoms of Townes-Brocks syndrome include kidney abnormalities, subtle to profound hearing loss, eye abnormalities, foot abnormalities, and genital abnormalities. About 10% of people with Townes-Brocks syndrome have a mild intellectual impairment or learning difficulties.
A collection of abnormalities affecting the kidneys or other organs of the urinary tract is congenital anomalies of kidney and urinary tract. The bladder, the tubes that carry urine from each kidney to the bladder, and the tube that takes urine out of the bladder are all examples of the urinary tract that may be affected by the disease. One or two kidney or urinary tract abnormalities in people with CAKUT are present. Urinary tract infections can persist or a buildup of urine in the urinary tract, which can damage the kidneys or other organs. Severe, CAKUT, can cause life-threatening kidney disease and end-stage renal disease. CAKUT is often one of many signs of a disease that affects multiple organ systems.
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