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Testicular Cancer - DOAJ

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Last Updated: 05 August 2022

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Robotic retroperitoneal lymph node dissection for testicular cancer at a national referral centre

Abstract Objectives We want to know if robot-assisted retroperitoneal lymph node dissection can be done as a safe alternative to open RPLND in select patients with metastatic germ cell carcinoma cancer. Patients and methods This population-based prospective research was conducted at one of Sweden's two national referral centers for RPLND. Logical regression modeling was used to determine patients to open versus robotic RPLND. BMI 24 kg/m2, median, retroperitoneal tumour diameter of 18 mm, BMI 24 kg/m2, operative time 433 min, estimated blood loss 50 ml, length of stay 3 days were all three days. Four patients had Clavien'u2013Dindo grade 3 disorders, three of whom were chylousu2010-related. Conclusions According to this population-u2010 report, RPLND can be safely administered in at least one third of patients referred for an RPLND. When deciding on robotics versus open RPLND, the most important distinction maker may be Tumour size.

Source link: https://doi.org/10.1002/bco2.149


Molecular characterization of gastric adenocarcinoma diagnosed in patients previously treated for Hodgkin lymphoma or testicular cancer

Introduction to gastric cancer patients treated with radiotherapy for Hodgkin lymphoma or testicular cancer are at a risk of developing gastric cancer. This report will determine whether gastric adenocarcinoma following HL/TC therapy is molecularly different from gastric adenocarcinoma in the general population. Patients were diagnosed with t-GC u22655 years after undergoing HL/TC therapy. MLH1 promoter methylation was noted in 36% of MSI t-GCs, and 2/6 were explained by two somatic mutations in MMR genes, and 26% were explained by two somatic mutations in MMR genes. T-GC was more commonly sGS in HL/TC patients diagnosed before 1990 than after 1990. Conclusion Our results show that t-GCs are more frequent of the sGS subtype than p-GCs. The high incidence in HL/TC patients who were treated before 1990, a time period in which HL/TC treatments were more prevalent, has led to an association of t-GC of the sGS subtype with prior anticancer therapy.

Source link: https://doaj.org/article/993e724dfefc4d14804e1ac4835f79a6


A Machine Learning Algorithm for Predicting the Risk of Developing to M1b Stage of Patients With Germ Cell Testicular Cancer

Objection: Objective: Distant metastasis other than non-regional lymph nodes and lung, which has a significant effect on patients with germ cell tumor cancer survival is poor. paraphrasedoutput:Methods is a patient with GCTC who have died from the Surveillance, Epidemiology, and End Results databases. The intention of this study was to create a machine learning algorithm that could help with patient detection in early intervention of patients with GCTC who are inexperienced. The independent predictors of rising M1b stage risk were lymph node dissection, T stage, N stage, lung metastases, and distant lymph node metastases, according to multivariate logistic regression results. paraphrasedoutput:Conclusions-stage, not an determining factor in predicting the risk of producing the M1b stage of patients with GCTC, based on both the XGBoost and RF algorithms, produced stable and reliable prediction results in both the preparation and external validation groups.

Source link: https://doi.org/10.3389/fpubh.2022.916513


Public awareness of testicular cancer and testicular self-examination in academic environments: a lost opportunity

BACKGROUND: Although testicular cancer is the most common cancer among 18-to-five-year-old males, healthcare professionals rarely teach testicular self-examination techniques to patients, potentially missing opportunities for early detection. OBJECTIVE: Our goal is to determine the level of knowledge of testicular cancer and the prevalence of testicular self-examination in academic settings in order to implement appropriate interventions. METHOD: A cross-sectional survey was administered to 750 consecutive males aged 18-50 years in three separate tertiary institutions in Port Harcourt from October 2008 to April 2009. Almost all of the respondents were unaware that testicular lumps could be signs of cancer. "Understand male men are not aware of their risk of testicular cancer," few said they were "ever taught about testicular self-examination," the most common age group.

Source link: https://doi.org/10.1590/S1807-59322011000700001


Metastatic testicular cancer presenting with hematuria and flank pain

Testicular cancer accounts for 1% of male neoplasms and 5% of urological tumors. At diagnosis, 55% of patients with nonseminoma TC have stage I disease. The patient himself or its companion by palpation usually has a palpable testicular mass. We describe a case of a 25-year-old male patient with atypical symptom: hematuria, hydronephrosis, and direct infiltration of the ureter by the retroperitoneal mass, mimicking renal colic. A retroperitoneal lymph node dissection was done after the medicalization.

Source link: https://doi.org/10.4103/UA.UA_63_20


A Cross-Sectional Analysis of Testicular Cancer Symptom Recognition and Stage of Diagnosis

To help develop a more specific list of potential testicular cancer signs that may help physicians diagnose the disease earlier, doctors must continue investigating the connection between atypical symptom logging and stage diagnosis. A cross-sectional research was conducted to determine potential correlations between TC symptom onset and diagnosis. This review sought to determine whether such patient-driven experiences might be able to prompt medical attention for testicular health issues. Experiencing hot flashes or having no symptoms had a positive correlation with late-stage illness, but change in form had a significant negative correlation with later-stage diagnosis. Although the logistic regression model explained little variation in the results, it was nonetheless statistically significant. These rare signs can be another route in the TC diagnostic process if you happen with other uncommonly reported illnesses.

Source link: https://doi.org/10.1177/15579883221104900


Inflammatory Biomarkers for Outcome Prediction in Patients With Metastatic Testicular Cancer

Male young adults have Germ cell tumors, which are the most common malignant tumors. The results of metastatic germ cell tumor patients have dramatically improved, and overall cure rates now exceed 90%. The issue of prognostic causes is more difficult after first-line chemotherapy 20%-30 percent of patients relapsed, and for these patients, the issue of prognostic factors is more difficult. Cancer-related systemic inflammation, tumorigenesis, and cancer progression have been shown to be correlated with cancer-related systemic inflammation, tumorigenesis, and cancer progression. This study explored the prognostic effects of inflammatory markers obtained in regular blood draws in GCT patients.

Source link: https://doi.org/10.3389/fonc.2022.910087


The Connection Between Testicular Cancer, Minority Males, and Planned Parenthood

Testicular cancer is the most common neoplasm diagnosed in males aged 15 to 40 years. Planned Parenthood Federation of America offers a number of male reproductive/sexual health care services, including TCa screening and referral services. An ecological investigation was conducted using data from the United States Cancer Statistics, American Community Survey, and PPFA websites to determine the effect of TCa on minority males, analyze connections between PPFA programs and minority males, and identify future pitfalls concerning TCa testing needs. Given the growing TCa outcomes in minority males, increasing PPFA men's health services is vital in finding inexpensive ways to help diagnose testicular abnormalities that are early stage or carcinoma in situ. Many young at-risk males have no means to obtain TCa screening services.

Source link: https://doi.org/10.1177/1557988318786874


Perceptions of Testicular Cancer and Testicular Self-Examination Among College Men

Testicular self-exam is a common method to avoid late-stage diagnosis of testicular cancer. 300 university males were interviewed on their experiences of vulnerability, perceived value of health promotion strategies, TC/TSE information, and preference for health promotional data in this research. Participants responded with skepticism about health promotion strategies, particularly TSE, and expressed a strong desire to implement health promotion practices, with several reporting very encouraging responses. Participants said that they liked personalized, tailored information to learn about TC and TSE. Knowledge and awareness of TC/TSE, perceived value of health promotion, and attitudes are all key predictors of intention to perform TSE. Among generalized pamphlets, personalized messages, and group training sessions, there were significant predictors of promotional tool preferences. The researchers recommend that researchers tailor promotional messages in TC/TSE awareness campaigns with an individual's chosen for marketing tactic.

Source link: https://doi.org/10.1177/1557988311409023

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions