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Systemic lupus erythematosus is a chronic illness that causes inflammation in connective tissues, such as cartilage and blood vessels, which give strength and flexibility to organs throughout the body. SLE is one of a large group of disorders associated with autoimmunity that occur when the immune system attacks the body's own tissues and organs. Extreme exhaustion, a vague sense of discomfort or illness, fever, appetite loss, and weight loss may have started as extreme tiredness, a vague sense of pain or illness. Joint pain, commonly affecting both sides of the body, joint pain, muscle pain, and weakness are all common problems for people with joint pain, as well as muscle pain and weakness. In SLE, skin disorders are common. Calcium deposits under the skin, damaged blood vessels in the skin, and tiny red spots called petechiae are all typical skin problems in SLE. In the moist lining of the mouth, nose, or, less commonly, the genitals, affected individuals may also suffer hair loss and open sores. About a quarter of people with SLE suffer kidney disease, according to the CDC. Heart problems may also occur in SLE, such as inflammation of the sac-like membrane around the heart and abnormalities of the heart valves, which regulate blood flow in the heart. Heart disease caused by fatty buildup in the blood vessels, which is extremely common in the general population, is even more prevalent among people with SLE. People with SLE have episodes in which the illness gets worse and then get better, while others with good health have episodes.
Deficiency component 2 of Complement is a condition that causes the immune system to malfunction, resulting in a form of immunodeficiency. People with complement component 2 deficiency have a dramatic risk of recurrent bacterial infections, particularly in the lungs, the membrane surrounding the brain and spinal cord, and the blood – which can be life-threatening. Complement component 2 deficiency is also associated with an elevated risk of experiencing autoimmune disorders such as systemic lupus erythematosus or vasculitis. SLE is a condition that causes impairments in the physical and mental aspects. Between ten percent and 20 percent of people with SLE have a defect. Females with complement component 2 deficiency are more likely to have SLE than males, but it is also true for SLE in the general population. Deficiency severity of complement component 2 deficiency varies widely.
Antiphospholipid syndrome is an illness that is characterized by an elevated risk of forming abnormal blood clots that can block blood vessels. If a blood clot exists in the vessels in the brain, blood circulation in the blood vessels is reduced and can lead to stroke. In addition, women with antiphospholipid syndrome are more vulnerable to experiencing a thrombosis during pregnancy than at other times in their lives. Infants of mothers with antiphospholipid syndrome may be small and underweight at birth, while pregnant infants with antiphospholipid syndrome may be small and underweight. Other signs and symptoms of antiphospholipid syndrome affecting blood cells and vessels include a reduced number of cells involved in blood clotting, a red blood cell shortage, and a purplish skin discoloration caused by abnormalities in the tiny blood vessels of the skin. People with antiphospholipid syndrome have thromboses in multiple blood vessels throughout their body.
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