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Syphilis - Springer Nature

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Last Updated: 21 June 2022

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Unexpected Reason for Non-healing Oral Ulcers: Syphilis

Syphilis is a sexually transmitted infectious disease caused by Treponema pallidum and characterized by a diverse and variable clinical presentation. Patients were found with non-healing oral ulcers in three cases, according to our article. Enhanced spirochetes within the epithelium were identified within the epithelium, with further diagnostic confirmation assay by serum T. pallidum particle agglutination assay. If clinical history influences the differential diagnosis, or if other medical conditions support this hypothesis, it is likely that immunohistochemistry for T. pallidum in oral biopsies from non-healing ulcers is critical.

Source link: https://doi.org/10.1007/s12105-021-01348-y


A cross-sectional survey on attitudes of men who have sex with men towards anal self-examination for detection of anal syphilis

According to reports, men who have sex with men practising receptive anal sex are more likely to experience secondary syphilis, meaning primary anorectal lesions are unlikely to be missed. 66% who had never tried ASE, 68% would consider doing ASE in the future with a favored median frequency of 2 times per 4 weeks, while ASE-based ASE men were still learning ASE at median 1 per 4 weeks. Almost two-thirds of MSM who had never attempted ASE were ready to implement ASE methods in the future.

Source link: https://doi.org/10.1038/s41598-022-12881-3


Health Information and Monitoring of Sexually Transmitted Infections (SIM study): a single-center, parallel, three-arm randomized controlled trial protocol for enhancing adherence to syphilis treatment and follow-up

Background Syphilis has recently resurfaced as a significant public health issue. Since the 2000s, isolated syphilis outbreaks in North America, Europe, and Australia have thrived; in Brazil, increases in both congenital and acquired syphilis have increased. Cell phones have been used to successfully drive behaviour change, and they can also have a positive effect on disease prevention and follow-up adherence in patients with infectious diseases. The aim of this clinical trial is to evaluate treatment and monitoring methods in patients with syphilis, including a telephone call and a game in a smartphone app, and at public health centers. Patients with a confirmed diagnosis as a result of VDRL studies will be randomized to one of three arms: telephone, smartphone game, or a traditional in-person sequel. Conclusion If we find differences in performance, a major reform in the current Brazilian health policy guidelines could be needed, potentially impacting current Brazilian health policy goals.

Source link: https://doi.org/10.1186/s13063-022-06383-w


Coerced syphilis self-testing among men who have sex with men: a nationwide cross-sectional study in China

Background Background: In several low- and middle-income countries, the test result remains low among men who have sex with men. Self-testing by Syphilis is an effective way to increase syphilis testing coverage. This report sought to investigate the prevalence, pattern, and causes of coerced syphilis self-testing among MSM in China's MSM. Conclusions Overall, 174 MSM were recruited in this survey, 31 men reported never experiencing syphilis self-testing coercion, and 31 men said ever experiencing syphilis self-testing coercion. Verbal assault and threats to end a marriage were two of the most common methods of coercion before syphilis self-testing. According to multivariable logistic regression, men who used condoms inconsistently in the last three months, ever used opioids before or during sex, ever had group sex with males and commercial sex were more likely to experience syphilis self-testing coercion. Conclusions Coerced syphilis self-testing was widespread among MSM in China. In China, MSM has a vital role to minimize coerced syphilis self-testing.

Source link: https://doi.org/10.1186/s12879-022-07476-2

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions