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This research was designed to determine whether prescribed NSAIDs were related to stress fracture diagnoses among US Army soldiers. We also wanted to see if acetaminophen, an analgesic alternative to NSAIDs, was linked to stress fracture risk. We found soldiers with a diagnosis of stress fracture in their work, and we chose four controls per case matched on length of military service. With adjustment for sex, conditional logistic regression was used to determine incident rate ratios for stress fracture. With a 2. 2-fold rise in stress fracture risk among the general Army population and acetaminophen prescription, there was a 2. 9-fold increase and acetaminophen prescription. During BCT, the threat was more than fivefold greater in soldiers prescribed NSAIDs and more than fourfold greater in soldiers prescribed acetaminophen. Bone and Mineral Research, published by Wiley Periodicals, Inc. on behalf of American Society for Bone and Mineral Research.
Source link: https://www.osti.gov/biblio/1623566
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