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Abstract Background Obstructive Sleep Apnoea is a risk factor for cardiovascular disease and Type 2 diabetes. While observational studies showed that OSA therapy might reduce CVD and T2D, some RCTs were unable to support these findings in part due to a lack of adherence to continuous positive airway pressure. Physical fitness has been shown to have a positive effect on CVD and the risk of T2D independent of the disease's weight, and can therefore provide additional health benefits to patients with OSA, whether or not adherent to CPAP. The secondary aim was to determine the effect of the PA intervention on OSA severity. In participant's home environment, a 12-week daily PA intervention was made; PA was tracked via text and validated by objective PA techniques. Future trials will determine whether PA can eliminate the burden of OSA-related comorbidities.
Source link: https://doi.org/10.1186/s13102-020-00195-8
Background: Multiple academic departments are involved in the delivery of obstructive sleep apnoea therapy in Japan. Inconsistent findings regarding depression and OSA have been published. Methods: This cross-sectional survey compared newly diagnosed OSA patients at two outpatient sleep apnoea units in Shiga Prefecture, Japan, one associated with the psychiatry department and the other with the otolaryngology department. Conclusions: The psychiatry unit was more patients referred by psychiatrists than those with the otolaryngology unit. Patients with moderate to severe OSA had lower PHQ-9 results than those with no to mild OSA. Patients with sleeplessness, insomnia, and depressive signs were more likely to attend a sleep outpatient unit affiliated with a psychiatry service, according to the study, while those with snoring and sleep apnoea were more likely to attend one affiliated with an ophthalology department. OSA severity was negatively related to depressive signs, and depressive symptoms were negatively correlated with depressive symptoms.
Source link: https://doi.org/10.3390/ijerph19095007
The antioxidant enzyme paraoxonase-1, as well as monitoring the immune defense systems and the effects of drugs in OSA patients could be useful. The serum concentrations of PON-1 in OSA patients and non-OSA controls were investigated, by way of systematic review and meta-analysis. The meta-analysis included eleven studies in 429 OSA patients and 258 non-OSA controls. The pooled serum PON-1 levels were significantly lower in OSA. PON-1 studies are also needed to establish the clinical use of PON-1 products for risk stratification and monitoring in OSA patients.
Source link: https://doi.org/10.3390/antiox11040766
In patients with OSA, we wanted to find out the consequences of respiratory muscle conditioning. A review of research that included respiratory muscle exercise in OSA patients was reviewed. In the results analysis, eight papers involving 210 patients were included in the data synthesis of the 405 findings published by the initial search. We found significant rise in Epworth sleepiness scale in 4. 45 points, in Pittsburgh's sleep quality index of 2. 79 points, and maximum inspiratory pressure of 29. 56 cmH2O. IMT improves sleep quality, sleep quality, and inspiratory strength in patients with OSA.
Source link: https://doi.org/10.3390/clockssleep4020020
Obsstructive sleep Apnea is a term that describes dentists' knowledge and attitudes in Tana Toraja and North Toraja's districts. Methods: An online questionnaire was sent to all dentists registered at the Toraja branch of PDGI, using the Google Forms platform, a questionnaire that was adapted from the International Dental Journal 2021 entitled Knowledge and attitude of dentists towards obstructive sleep apnoe. These results show that dentists in Tana Toraja and North Toraja, as well as hospitalization in OSA management, are seeking more education and clinical experience in order to maximize patient satisfaction and minimize adverse outcomes.
Source link: https://doi.org/10.35856/mdj.v11i1.516
With and without obstructive sleep apnoea, we compared cardiac autonomic function in paroxysmal atrial fibrillation patients. PAF patients with PAF recruited at two tertiary centers were recruited by two tertiary centers, according to Case Control. Cardiac autonomic function was determined by heart rate variability and revealed by sleep stage for patients with and without OSA. In either REM or non-REM sleep, PAF patients with and without OSA did not differ between PAF patients with and without OSA. During non-REM sleep in PAF patients with OSA, cardiac parasympathetic modulation increased cardiac arrest and reduced cardiac sympathetic modulation, according to Frequency-domain analysis during non-REM sleep. During REM sleep, there were no differences in HRV values. Conclusions This is the first investigation into HRV in PAF patients with and without OSA. During steady-state non-REM sleep, this study shows a steady rise in parasympathetic nervous modulation and relative decrease in sympathetic modulation in PAF patients with OSA.
Source link: https://doi.org/10.1007/s10840-022-01202-3
Background: Obstructive sleep apnoea can play a role in cancer risk, according to increasing evidence; however, no studies on continuous positive airway pressure therapy on cancer incidence are available. We investigated whether adherence to CPAP therapy was associated with a decrease in all-cancer incidences in comparison to those with non-adherent patients with OSA. We included patients who were not recommended CPAP for OSA, had no history of cancer before the diagnostic sleep study, or during the first year of CPAP. To determine the effect of CPAP adherence on cancer risk, a propensity score inverse likelihood of treatment weighting analysis was conducted. The final weighted version showed no significant effect of CPAP compliance on all-cause cancer risk. Conclusions Adherence to CPAP therapy in OSA patients was not associated with a decrease in all-cancer incidences. It's likely that adherent CPAP therapy of OSA can minimize the risk of particular cancer sites and specific cancer sites should be investigated.
Source link: https://doi.org/10.1183/13993003.01935-2021
We explore the benefits and feasibility of this new strategy in an AF outpatient clinic. Methods and findings 1. 3. Patients accepted for AF catheter ablation procedures without prior SDB diagnosis were digitally referred to a virtual SDB administration pathway and told to use WatchPAT-ONE for one night. The average time from digital consultation to finalization of the sleep study findings was 18 [11–24] days. Patients with SDB were given more cardiovascular medications and high body mass indices as a result of their elevated body mass indices. Conclusion This unique virtual AF management system enabled remote SDB testing in AF outpatient clinics with a short time to diagnosis and high patient satisfaction. The results of Structured SDB testing revealed a high percentage of previously unknown SDB in AF patients undergoing AF ablation.
Source link: https://doi.org/10.1093/europace/euab229
Abstract Aim The aim is to investigate the effect of the cervical headgear on the growth of obstructive sleep apnoea and subsequent oropharyngeal dimensions. Obstructive sleep apnoea, sleep disorders, pharyngeal measurements, and headgear were among the search keywords that included obstructive sleep apnoea, sleep disorders, pharyngeal measurements, and headgear. According to one review, headgear therapy may have an effect on apnoeic indices, while two others reported pharyngeal airway dimensions following the use of headgear alone or in combination with an activator unit. After headgear or activator use, the posterior airway space was similar, but combined headgear-activator therapy resulted in an increase in posterior pharyngeal area, relative to isolated fixed appliance therapy. Prospective controlled or randomised controlled trials are deemed appropriate to collect evidence on the effects of headgear therapy on sleep apnoea or pharyngeal airway measurements.
Source link: https://doi.org/10.21307/aoj-2020-076
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