Advanced searches left 3/3

Sleep Apnea - Crossref

Summarized by Plex Scholar
Last Updated: 12 January 2023

* If you want to update the article please login/register

Obstructive Sleep Apnea is Associated with Polycythemia in Hypogonadal Men on Testosterone Replacement Therapy

Abstract Background Polycythemia is a well-known side effect of testosterone replacement therapy and it correlates with elevated T levels. There is also a well-established association between obstructive sleep apnea and the formation of polycythemia, which adds to long-term cardiovascular morbidity. In the case of polycythemia development, the interaction between TRT and OSA is still unclear. Aim Of This study was to retrospectively assess the association of OSA and secondary polycythemia in hypogonadal men receiving TRT. Outcome The main outcome of this analysis was the connection between OSA and polycythemia in hypogonadal men on TRT. In hypogonadal men, the concomitant diagnosis of OSA showed a strong positive correlation between polycythemia and the concomitant diagnosis of OSA. In the final cohort, there were 37 men on TRT with polycythemia and OSA, with a median age of 59. 2 u00b1 6. 0, and median time from TRT initiation to polycythemia diagnosis of three years, with median age of 59. 2 — 32. 4 u00b1 6. 0. In 58% of men, all patients with OSA were given continuous positive airway pressure with poor outcomes. BMI was the only risk factor strongly associated with OSA in hypogonadal men on TRT with polycythemia in hypogonadal men on polycythemia. A diagnosis of OSA should be strongly considered in hypogonadal men on TRT who experience secondary polycythemia. Conclusions In this prospective single-center cohort, polycythemia in hypogonadal men on TRT was linked to an elevated risk of OSA.

Source link: https://doi.org/10.1016/j.jsxm.2020.03.006


Assessment of Obstructive Sleep Apnea among Adult Hypertensive Patients on Follow-up at Jimma Medical Center

Introduction: Obstructive Sleep Apnea is a condition caused by the repetitive collapse of the upper airway during sleep. The pathophysiology of health conditions related to OSA is most strongly correlated to irregular hypoxia, which results in cell function impairment. Obsea in adult hypertensive patients on a sequel to Jimma Medical center in 2020 was aimed at assessing obstructive sleep apnea among adult hypertensive patients. Our baseline patients who attended the JMC's regular follow-up clinic were our baseline populations, while others who gave their consent and fulfilled our inclusion criteria during the study period were eligible as research participants. Result: A total of 291 adult hypertension patients on follow-up care at the JMC were included in the study, which included 155 men and 136 women. 187 of the 291 hypertensive patients screened for OSA using the STOP-Bang questionnaire revealed 187 of the patients as high risk of OSA.

Source link: https://doi.org/10.2174/1573398x18666220915111251


Application of drug-induced sleep endoscopy in predicting the outcomes of velopharyngeal surgery in adult patients with Friedman stage II and III obstructive sleep apnea syndrome

Objectives of this research The aim of this review was to determine the predictive value of drug-induced sleep endoscopy in adult patients with Friedman stage II and III obstructive sleep disorder syndrome. Methods A retrospective review of a total of 39 male OSAS patients with Friedman stage II and III was retrospectively reviewed. During pre-operative DISE examinations, all 39 patients developed complete velopharyngeal airway collapses. Responders and non-responders' glossopharyngeal airway collapse severity was significantly different between responders and non-responders. Treatment outcomes were independently predictive of treatment outcomes, according to the velopharyngeal airway collapse pattern and GA-CD. Patients with non-lateral VA-CP and grade II GA-CD had a significantly lower surgical success rate than those without a prescription. Conclusions The VA-CP and GA-CD findings in DISE are both highly useful in predicting the outcome of velopharyngeal surgery in patients with Friedman stage II and III OSAS patients. Patients with lateral VA-CP and grade I GA-CD are both eligible candidates for velopharyngeal surgery.

Source link: https://doi.org/10.3389/fneur.2022.1049425


Capacitively-Coupled ECG and Respiration for Sleep–Wake Prediction and Risk Detection in Sleep Apnea Patients

Patients of obstetric sleep apnea will greatly benefit from an improved home diagnosis, in which detection of wakefulness is crucial. The data coverage of ccECG and ccBioZ was determined by signal quality indicators, determined by the first, or ccBioZ. The data contained 187 PSG recordings of suspected OSA patients, 36 of which were recorded simultaneously with PSG, ccECG, and ccBioZ, illustrating a total of 187 PSG recordings of suspected OSA patients. Secondly, the use of the sleep-u2013wake classifier increased as it became a unimodal network only requiring respiratory input. With PSG respiration, a Cohen-u201d kappa of 0. 39 and using ccBioZ in a u03ba = 0. 23, a woke wake estimate on u201cTestu201d showed a Cohen'u2019s kappa of 0. 39 and using ccBioZ in u203ba = 0. 23. Using ccBioZ, the OSA risk model identified vulnerable OSA patients with a u03ba of 0. 61 for PSG respiration and a u03ba of 0. 39 for ccBioZ. This is one of the first studies to perform sleep-wake testing in suspected OSA patients and to identify high risk OSA patients based on ccBioZ.

Source link: https://doi.org/10.3390/s21196409


Functional Outcomes in Patients With Obstructive Sleep Apnea Residing in Southeastern Mexico

Patients with obstructive sleep apnea have a variety of and non-specific clinical presentations that can have a huge effect on their sleep quality and functional outcomes. paraphrasedoutput:Methods is a cross-sectional, descriptive study that was based on adult patients in southeastern Mexico who required respiratory polygraphy as a result of suspected OSA. This research sought to identify the signs of OSA, excessive daytime sleepiness, anxiety, and sleep quality, as well as clinical factors that may be responsible for poor functional outcomes in OSA patients. Effects A total of 199 patients with apnea index > 5 h -1 were included, as the dependent variable. Afnea, correlation, and univariate and multivariate logistic regression studies were conducted for these devices using the functional outcomes sleep questionnaire score 89. 5 points as the dependent variable. Conclusions Hypotheses and overactive daytime sleepiness were risk factors for poor functional outcomes in Mexican patients with OSA.

Source link: https://doi.org/10.17241/smr.2022.01473


Evaluating the Effects of Agomelatine on Polysomnography Parameters in Patients with Obstructive Sleep Apnea.

Obstructive sleep apnea is a common sleep disorder. Patients with sleep disorders using Melatonin-based drugs such as agomelatine may have calming effects on patients with sleep disorders. This research was conducted to determine agomelatine effects on polysomnography parameters in patients with OSA. Methods: Seventy patients 18 years of age or older with obstructive sleep apnea who were referred to the sleep clinic were evaluated in this randomized, parallel, and single-blind study. Patients in the agomelatine group received 50 mg agomelatine one hour before sleep for three nights in a row, one hour before bed, three nights before the polysomnography test, while the control group did not receive agomelatine. The sleep test results were compared between the two groups. Conclusions: Agomelatine administration in patients with OSA may increase total sleep time, sleep quality, and the number of patients with u2019 awakenings.

Source link: https://doi.org/10.18433/jpps33252


Obstructive Sleep Apnea and Risk of Miscarriage

This was a secondary report of a prospective observational cohort study of participants screened for sleep apnea during pregnancy using the Epworth Sleepiness Scale, Berlin Questionnaire, and a number of books related to sleep and napping. via Poisson regression, an association between responses to the sleep apnea screening questions with miscarriage of the index pregnancy was investigated. We found that gravidae who had risen scores on both the Epworth Sleepiness Scale and the Berlin Questionnaire were more likely to experience miscarriage than those who had raised scores on just one questionnaire or neither. Gravidae who said snoring or hypertension in the first trimester were more likely to have miscarriage than gravidae who did not. Both the Berlin Questionnaire and Epworth Sleepiness Scale were statistically significant with miscarriage prior to adjustment for confounding variables, as did snoring and hypertension.

Source link: https://doi.org/10.3390/reprodmed4010001


Insomnia in Patients Undergoing Hypoglossal Nerve Stimulation Therapy for Obstructive Sleep Apnea

Hypoglossal nerve stimulation is a drug used to treat obstructive sleep apnea patients with intolerance to positive airway pressure therapy. Following HGNS treatment, we investigated the effects of insomnia and heavy daytime sleepiness on polysomnography results. The preoperative ISI and postoperative AHI inverse correlations have emerged between preoperative ISI and postoperative AHI, u2206 AHI, and u2206 ODI. Nonetheless, the preoperative deterioration of patient-reported insomnia symptoms was also related to the respiratory PSG-outcomes after HGNS. In studies of EDS in OSA patients, especially those treated with HGNS, Insomnia should be considered.

Source link: https://doi.org/10.3390/biology12010098


Clinical-functional characteristics of children with asthma and obstructive sleep apnea overlap associated with attention deficit hyperactivity disorder: A cross-sectional study

Attention deficit hyperactivity disorder symptoms can be exacerbated by untreated OSA. This research was designed to determine the prevalence of ADHD in asthmatic children with OSA, as well as the relationship between asthma control and lung function in children with asthma and OSA. Methods According to the Global Initiative for Asthma 2020, 96 children aged 6 to 15 years were diagnosed with asthma, with asthma in this report. In the non-OSA asthmatic group, the inattentive ADHD subtype was significantly lower than in the OSA asthmatic group. Children with poorly controlled asthma had a significantly higher risk of OSA than children with well-controlled asthma. Allergic rhinitis raised the chances of having OSA in asthma patients with asthma [OR: 8. 217; p 0. 05]. ADHD may have a higher incidence in children with OSA. Hence, prompt diagnosis of OSA will result in a more effective asthma control plan in asthma patients.

Source link: https://doi.org/10.3389/fneur.2022.1097202


Development and Internal Validation of a Prediction Model for Surgical Success of Maxillomandibular Advancement for the Treatment of Moderate to Severe Obstructive Sleep Apnea

The Maxillomandibular advancement has been shown to be the most effective surgical therapy for obstructive sleep apnea. Despite high success, there are patients who are classified as non-responders to MMA. This research was intended to create, internally validate, and calibrate a prediction model for surgical success in patients with OSA in order to triage and advise these patients on their prognosis of MMA before surgery. Methods: Patients with moderate to severe OSA were included in a retrospective cohort study that included patients that had undergone MMA for moderate to severe OSA. Significant independent predictors of the model were Anterior's lower face height, superior posterior airway space, age, and a central apnea index 5 events/hour sleep. The latest predictive metrics for determining in and out of surgical success were 0. 21 and 0. 32, respectively.

Source link: https://doi.org/10.3390/jcm12020503

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions