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Skin Cancer - DOAJ

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Last Updated: 27 April 2022

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Non-melanoma skin cancer activity during the COVID-19 pandemic- A single UK tertiary centre experience

During the pandemic's first wave rise and peak, we retrospectively examined all patients who underwent a skin excision under local anaesthetic that revealed the presence of a basal cell carcinoma or squamous cell carcinoma on histopathological examination as a NMSC during the COVID-19 period, with a 158% rise in patients with excision of lesions identified on histopathological examination as a NMSC. With the introduction of a more effective approach to the NMSC service, five of these patients' further management changes were able to be useful service enhancements at this moment.

Source link: https://doi.org/10.1016/j.jpra.2021.04.001


Novel Methacrylate-Based Multilayer Nanofilms with Incorporated FePt-Based Nanoparticles and the Anticancer Drug 5-Fluorouracil for Skin Cancer Treatment

Despite medical advancements, skin-associated disorders persist to pose a unique challenge to physicians around the world. Skin cancer is one of the most common forms of cancer, with more than a million new cases reported each year. For the treatment of ranostic skin cancer treatment, the aim of our research was to produce novel multilayer nanofilms made of a blend of polyhydroxyethyl methacrylate, polyhydroxypropyl methacrylate, sodium deoxycholate, polyhydroxypropyl methacrylate, sodium deoxycholate, and a potent anticancer drug. Finally, the safety of skin cancer therapy was tested on our own basal-cell carcinoma cell line, which was confirmed.

Source link: https://doi.org/10.3390/pharmaceutics14040689


Rosmarinus officinalis L. Leaf Extracts and Their Metabolites Inhibit the Aryl Hydrocarbon Receptor (AhR) Activation In Vitro and in Human Keratinocytes: Potential Impact on Inflammatory Skin Diseases and Skin Cancer

Aryl hydrocarbon receptor activation by environmental agents and microbial metabolites may have been responsible for a sequence of skin diseases. Naturally, it would be vital to find natural compounds that could inhibit AhR activation by microbial origins as 6-formylindolo[3,2-b]carbazole, indirubin, and pityriazepin, or the prototype ligand 2,3,7,8-tetrachlorodioxin. In the presence of [3 H]TCDD, five different dry Rosmarinus officinalis L. extracts were apologetic for their role as antagonists of AhR ligand binding with guinea pig cytosol. Against TCDD, FICZ, PZ, and IND, the methanolic ROE was even more impressed with CYP1A1 mRNA gene induction by using RT-PCR in human keratinocytes. At 100 ppm, all assayed ROE extracts demonstrated similar dose-dependent effects with almost complete inhibition of AhR activation by TCDD. TCDD and the Malassezia metabolites FICZ, PZ, and IND inhibit AhR activation by TCDD and IND.

Source link: https://doi.org/10.3390/molecules27082499


An Exploration of the Use and Impact of Preventive Measures on Skin Cancer

Background: Skin cancer is the most common form of cancer, and both clinical and epidemiological studies show that cumulative solar doses correlates to skin cancer. Methods: This research analyzed results from the National Health and Nutrition Examination Survey (2015–2016 cycle to determine the relationship between three preventive steps with skin cancer. Conclusion: Sunscreen use was correlated with a lower risk of skin cancer, while long-sleeved shirts and staying in the shade were not significantly related to lower skin cancer risk, meaning that these steps may not be as efficient as sunscreen for preventing skin cancer. These findings will help guide future education and research into skin cancer prevention, as well as suggesting the creation of male-oriented services to eliminate gender in using sun-protection techniques.

Source link: https://doi.org/10.3390/healthcare10040743


A Qualitative Needs Analysis of Skin Cancer Care from the Perspectives of Patients, Physicians, and Health Insurance Representatives—A Case Study from Eastern Saxony, Germany

Skin cancer is one of the most common cancers worldwide, and the number of patients is steadily increasing. For prevention, early detection, and new complex systemic therapies, skin cancer care requires more interdisciplinary collaboration. However, the introduction of innovative medical care in rural areas with an older than average, multimorbid population, with limited mobility, and long distances from medical centers is a significant challenge. The aim of this research was to find indicators to establish a regional health network for integrated skin cancer care. To capture the viewpoints of various stakeholder groups, we conducted two focus groups with twenty skin cancer patients and their families, a conference with eight doctors, and three semi-structured interviews with health insurance company representatives. Our report should promote and promote as a result of the fact that all patients receive guideline-based therapy, regardless of where they live.

Source link: https://doi.org/10.3390/curroncol29040212


Reconstruction of Large Facial Defects via Excision of Skin Cancer Using Two or More Regional Flaps

Background Notes: Background Free-flap surgery and skin grafting can be used to restore significant facial scarring after skin cancer removal by Mohs micrographic surgery. Both these two procedures may cause poor postsurgical patient satisfaction with aesthetics, and free-flap surgery may result in undue burden for the majority of skin cancer patients of advanced age. Hence, the authors investigated the results of large facial defect reconstruction using multiple flaps. Methods 7 patients under medical care at Pusan National University Hospital between January 2013 and December 2015 evaluated 7 patients for significant facial abnormalities related to basal cell carcinoma. Reconstruction after skin cancer treatment using MMS resulted in positive results, despite preventing aesthetic issues, with two or more flaps for significant facial defects. Practitioners should consider using multiple flaps when selecting a reconstruction strategy for large facial scars after skin cancer surgery.

Source link: https://doi.org/10.5999/aps.2017.44.4.319


Biomimetic Nanoscale Materials for Skin Cancer Therapy and Detection

Skin cancer has emerged as one of the world's most common disorders, with major effects on public health and the economy. Nanotechnology-based cancer therapy techniques are popular because they enable the safe transport of medications and other biologically active chemicals to specific tissues while minimizing harmful effects. Multiple skin cancer treatments and diagnosis can be included in the current review. For the prompt diagnosis of this type of disease, there are several skin cancer indicators available. Traditional approaches to skin cancer diagnosis are explored, as are their flaws.

Source link: https://doi.org/10.1155/2022/2961996


A Comprehensive Evaluation of Health-Related Life Quality Assessment Through Head and Neck, Prostate, Breast, Lung, and Skin Cancer in Adults

Health care teams' process in designing a care and assistance plan and understanding the patient's needs can be aided by health assessment results. Comprehensive and detailed information about the Quality of Life of cancer patients contributes to the development and management of cancer patient care. Patients of Cancer are susceptible to a variety of health problems, including pain and various physical and mental disorders that negatively influence their Quality of Life. In this series, we explored cancer and the impact that this illness can have on cancer patients' Quality of Life.

Source link: https://doi.org/10.3389/fpubh.2022.789456


Herpes vegetans on the shoulder mimicking nonmelanoma skin cancer

Although herpes simplex virus type 2 infections predominantly occur in the oral or anogenital area, our patient presented with ulcerated vegetative plaques on the shoulder presenting clinical features with nonmelanoma skin cancer. When faced with unusual ulcerated or verrucous lesions, dermatology specialists should include HSV-2 in the differential diagnosis.

Source link: https://doi.org/10.1016/j.idcr.2022.e01502


Sun-protective behaviors in populations at high risk for skin cancer

Melanoma, a subtype of skin cancer that can be fatal if not detected and treated early, is the second most common cancer among adolescents and young adults aged 15 to 29 years. UV light from solar radiation and tanning beds is the most important carcinogen responsible for skin cancer origins. A plausible explanation is the lack of behavioral change in the populations at risk; in this review article, we investigate sun-protective behavior in the four high-risk skin cancer organizations, skin cancer survivors, individuals with a family history of melanoma, individuals with physical characteristics associated with skin cancer risk, and organ transplantation patients.

Source link: https://doaj.org/article/a18713a08b2f48d4ba8d65afdce1778d

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions