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Skin Cancer - Crossref

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Last Updated: 27 November 2022

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The Human Microbiota and Skin Cancer

Skin cancer is the most common form of cancer in the United States, with increasing incidence globally. Little is known about the role of microbiota in skin cancer, but with the documented connection between microbial dysbiosis and inflammation, as well as the fact that microbiota modulates UV-induced immunosuppression, research connecting the two have emerged. We present a comprehensive review of the most important literature on human microbiota, especially the skin microbiota and skin cancer in this article.

Source link: https://doi.org/10.3390/ijms23031813


Skin Cancer Management: Current Scenario And Future Perspectives

UV radiation is the most common cause of skin cancer. Sunlight was the most common cause of skin cancer in the twentieth century. paraphrasedoutput:cutaneous melanoma was largely due to repeated exposure to the sun, according to a new breed of sun exposure, whereas keratinocyte carcinomas occurred as a result of progressive sun exposure. To some degree, radiotherapy has been shown to cure skin cancers, to a certain extent, but the results are uncertain since it is dependent on the patient's type of tumour and surgical treatment. Due to the various risks of skin cancer treatment and severity, there is a need for cost-effective, novel, and efficient treatment. Several nanocarriers, magnetic nanoparticles, gold nanoparticles, carbon nanotubes, etc. , are potential agents in the diagnosis and prognosis of both non-melanoma and melanoma skin cancer. The investigation also addresses the role of various nanocarriers in treating and diagnosing skin cancer.

Source link: https://doi.org/10.2174/1574886317666220413113959


The Effect of Irradiation on the Skin upon Breast Cancer Radiotherapy Studied by FTIR Spectroscopy

Breast cancer affects the female population around the world. After radical mastectomy or conserving surgery, radiotherapy is part of the therapeutic modality in breast cancer treatment. On a molecular level at the very early stages, the FTIR spectroscopic u201cmarker bandsu201d will lead us to investigate skin damage caused by ionizing radiation and skin interactions. Healthy breast skin was irradiated ex-vivo with a 4 Gy dose of a Gammachamber 4000A. As a result of free radicals as mediated products, the low-dose irradiation caused skin dehydration, collagen secondary structure changes, and improved glycation end products, according to the FT-IR spectra. In comparison to the smooth surface of the non-irradiated healthy skin, ImageJ's report revealed the prominent surface of the skin after RT irradiation.

Source link: https://doi.org/10.21926/obm.geriatr.2204215


Real-time high-resolution millimeter-wave imaging for in-vivo skin cancer diagnosis

Abstract High-resolution millimeter-wave imaging, with its high discrimination contrast and large penetration depth, can potentially provide inexpensive tissue diagnostic information noninvasively. In this report, we explore the use of a real-time HR-MMWI for in-vivo skin cancer diagnosis. Measurements revealed 136 benign and malignant skin lesions from 71 patients, including melanoma, basal cell carcinoma, squamous cell carcinoma, actinic keratosis, cutaneous keratosis, melanoma, dermatosis, angiokeratoma, solar lentigo, and seborrheic keratosis. Our results show that real-time millimeter-wave imaging can be used to distinguish malignant tissues from benign skin lesions with high diagnostic sensitivity comparable to clinical examination and other methods.

Source link: https://doi.org/10.1038/s41598-022-09047-6


Synergistic effect of plasma-activated medium and novel indirubin derivatives on human skin cancer cells by activation of the AhR pathway

As anti-cancer therapy, the use of cold atmospheric pressure plasma has become more important in recent years. Cell viability and cell adhesion were determined in combinatorial experiments with plasma-activated medium and KD87. We hypothesize a different mode of action of the indirubin derivatives in the two skin cancer cells due to a different expression of this receptor and subsequent transcription of gene expression in the two skin cancer cells, but not in A431 cells.

Source link: https://doi.org/10.1038/s41598-022-06523-x


Skin cancer outcomes and risk factors in renal transplant recipients: Analysis of organ procurement and transplantation network data from 2000 to 2021

Purpose: After patients have undergone renal transplantation, patients have the most common malignancy, according to Purpose. Through extensive research with a large sample size around the world, understanding the risk factors and outcomes of posttransplant skin cancer may help to develop effective patient surveillance and disease prevention strategies. The following risk factors for developing posttransplant skin cancer were: older age, male sex, Caucasian race, pre-transplant malignancy, polycystic kidney disease-related end-stage renal disease, T-cell depletion, and T-cell depletion induction, as well as tacrolimus/mycophenolic acid use. Independent risk factors for post-transplant skin cancer onset momentum were the Caucasian race and pretransplant malignancy. Conclusion Although posttransplant skin cancer is a leading cause of recipient death, there is little evidence regarding the patient and graft survival. Given the variability in risk factors for posttransplant skin cancer incidence, onset momentum, and mortality, personalized screening strategies could be useful to address the difficult problems faced by kidney transplant recipients.

Source link: https://doi.org/10.3389/fonc.2022.1017498


DUNEScan: a web server for uncertainty estimation in skin cancer detection with deep neural networks

Abstract The number of skin cancer detection applications has risen sharply in recent years. We're proud to announce DUNESCAN, a web server that performs an in-depth review of uncertainty in commonly used skin cancer classification schemes based on convolutional neural networks. Users can upload a skin lesion picture and then compares the mean and the variance estimates produced by a variety of new and traditional CNN models.

Source link: https://doi.org/10.1038/s41598-021-03889-2


Risk assessment of occupational skin cancer among outdoor workers in southern Spain: local pilot study

Objective Overexposure to ultraviolet radiation is the most common preventable cause of skin cancer. The purpose of this investigation is to establish occupational photoexposure and photosecurity among outdoor employees employed by a municipality in southern Spain. Results The median effective erythema dose during the working day was 379. 4 J/m 2, or 3. 8 standard erythema doses, was nearly three times higher than the recommended limits for an 8-hour workday. The presence of actinic lentigines, actinic keratoses, and skin cancer had been revealed by skin examination. A sunburn rate of 50. 0 percent was found on the CHACES questionnaire, with a sunburn rate of 50. 0 percent. Summary This is the first study to determine UV radiation exposure, occupational sun protection, sunburn, and actinic injuries of various outdoor workers in one of Spain's sunniest areas, and it highlights the need for effective measures to safeguard outdoor workers'u2019 health.

Source link: https://doi.org/10.1136/oemed-2022-108454

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions