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Simvastatin - Springer Nature

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Last Updated: 09 September 2022

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Simvastatin inhibits prostatic hyperplasia in rats with metabolic syndrome

Objects (Objects): The effects of metabolic syndrome induced by high fat diet in rats' model include prostate tissue and local inflammatory markers, as well as the protective effectiveness of statins against pathological changes of prostate. In the blank and saline subgroups of the HFD group, the level of serum lipid, prostatic weight, hyperplasia, as well as expressions of IL-6, TNF-u03b1 and IGF-1 were higher than those of the ND group. Simvastatin can reduce prostate hyperplasia by the removal of local inflammation in prostatic tissue.

Source link: https://doi.org/10.1007/s11255-022-03227-z

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions