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Schwannoma - DOAJ

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Last Updated: 18 September 2022

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A case of intestinal schwannoma initially suspected by transvaginal ultrasound

Schwannomas are peripheral nerve sheath tumors. Due to their low prevalence, only a few cases of colorectal schwannomas have been reported, which raises the diagnostic difficulty. When in the hands of properly trained professionals that perform systematized procedures, the goal of this case study is to explore the role of transvaginal ultrasound in various areas other than gynecologic disorders. A 56-year-old woman was consulted for postmenopausal genital bleeding. Transvaginal ultrasound is now one of the most commonly used and reliable diagnostic tools in the diagnosis of gynecological disorders.

Source link: https://doi.org/10.1016/j.radcr.2022.08.028


Vestibular schwannoma associated with neurofibromatosis type 2: Clinical course following stereotactic radiosurgery

In our tertiary referral center, we retrospectively reviewed the results of stereotactic radiosurgery in this population. MethodsWe investigated the results of stereotactic radiosurgery in this population. MethodsWe retrospectively reviewed NF2 patients treated with Gamma-Knife SRS for VS in our tertiary referral center. Longitudinal volumetric tests were performed for the tumor volume response of the 41 treated lesions following SRS. ResultsMost treated lesions showed good tumor control up to 85% at 60 months after SRS, at 60 months after SRS, with an observed volume increase of 14. 0% per year during the observation period. ConclusionsWhile patients with serviceable hearing can be appropriately handled by SRS, two patients on the treated side lost their hearing function within 24 months during the early follow-up period, but hearing function is not immediately beneficial in terms of preserving hearing ability.

Source link: https://doi.org/10.3389/fonc.2022.996186


Benign glandular schwannoma

We report a case of benign glandular schwannoma in a 63-year-old male who presented with a single subcutaneous mass on the left knee with no previous history of neurofibromatosis type 1. Some of the glands in this patient resembled sweat glands. These lining stromal spindle cells were positive for S-100 but not negative for EMA. EMA, especially at the luminal boundaries, were positive for EMA. They were also positive for pancytokeratin.

Source link: https://doaj.org/article/a5b3b63f19f3488c9f388f4e8ee5f7bc


Paraglottic space schwannoma: a case report and literature review

We herein report a case of a schwannoma arising from a rare larynx subsite as well as an anthology of laryngeal schwannoma. The case involved a woman with a 1-month history of globus pharyngeus and dysphagia without dysphonia. A large submucosal bulge toward the medial wall of the right pyriform fossa's right pyriform fossa's right pyriform fossa's medial wall was revealed by magnetic resonance imaging, extending the right false and true vocal cords and arye fold inward. The transcervical approach is a fast and less invasive treatment for laryngeal schwannoma present in the paraglottic space.

Source link: https://doi.org/10.1177/03000605221122497


Schwannoma mimicking ovarian malignancy

We discuss in this article a case of retroperitoneal schwannoma localized in the pelvic cavity, mimicking ovarian carcinoma. Magnetic resonance imaging revealed a solid left tumor in the small pelvis, posterior to the uterus, and was suspicious of an ovarian malign tumor. The diagnosis of schwannoma was confirmed by pathology examination of the pelvic mass. While prompt recognition of ovarian cancer is vital, understanding of processes that mimic ovarian tumors can help prevent potential misdiagnosis. The pelvis has a complex anatomy, and there are some imaging techniques that aid in determining the source of a mass, particularly in cases of masses opposing the ovary.

Source link: https://doi.org/10.1016/j.radcr.2022.08.014


Sciatic nerve schwannoma complicated by nerve bundle membrane effusion: Two case reports and a literature review

Schwannoma is a benign tumor that arises from Schwann cells in the peripheral nerve tunica or bundle of nerves and progresses along the nerve's longitudinal axis. Schwannoma can occur in several anatomic locations, but not so often in the sciatic nerve. Here, we report two cases of sciatic nerve schwannoma mixed with nerve bundle membrane effusion, and the relationship between the two conditions is uncertain.

Source link: https://doi.org/10.3389/fonc.2022.915982


Laparoscopic partial cystectomy through extraperitoneal space for primary bladder schwannoma

Abstract Background Schwannomas can develop in the body where nerve sheaths are present. Primary bladder schwannomas are extremely unusual, particularly primary bladder schwannomas. Case report The 39-year-old man's symptoms after the treatment of prostatitis for two weeks was not evidently improved, due to frequent urination and urgency for 1 month. A mass in the left side wall of the bladder with no boundaries and protruded outward from the bladder was shown by ultrasound and computed tomography. It was largely S100 protein positive, according to immunohistochemical staining. Conclusions Bladder schwannomas are medically uncommon benign bladder lesions with no apparent clinical signs.

Source link: https://doi.org/10.1186/s40001-022-00796-8


Quantitative Chemical Exchange Saturation Transfer Imaging of Amide Proton Transfer Differentiates between Cerebellopontine Angle Schwannoma and Meningioma: Preliminary Results

In evaluating malignant brain tumors, new research has shown the effectiveness of amide proton transfer -chemical exchange saturation transfer imaging in evaluating malignant brain tumors. From November 2020 to April 2022 pre-operation, we retrospectively evaluated nine patients with schwannoma and nine patients with meningioma who underwent APT-CEST MRI. MTR asym values below 0. 024 were 88. 9%, 77. 8%, 80. 0%, and 85. 5%, respectively, with diagnostic sensitivity, specificity, positive predictive value, and negative predictive values for MTR asym below the threshold of 0. 024. Our findings showed that MTR asym values on APT-CEST imaging could help distinguish patients with schwannomas from patients with meningiomas.

Source link: https://doi.org/10.3390/ijms231710187


Significance of Dosimetric Parameters in Patients Undergoing Gamma Knife Radiosurgery for Vestibular Schwannoma

Aim: This study will help identify the relevance of Conformity Index and Gradient Index in patients undergoing GKRS for VS, retrospectively, and re-assess the objectives. A dosimetric analysis of 112 patients of VS treated on a Gamma Knife Perfexion unit at our hospital over a three-year period was performed retrospectively. The patients' mean age at the time of GKRS was 48 years, and the median dose to the tumor margin was 13 Gy. The dosimetric parameters, such as Conformity Index and GI, were calculated using the dose-volume histograms and the volume analysis software included in the Leksell Gamma Plan using the TMR 10 algorithm. The mean GI was 0. 80 u00b1 0. 22, with the mean GI at 0. 80 0. 085. Conclusions: The dosimetric parameters can be used to determine the dose coverage and stability, as well as dose falls off outside the target.

Source link: https://doi.org/10.4103/jmp.jmp_5_22


Understanding the Molecular Mechanism of Vestibular Schwannoma for Hearing Preservation Surgery: Otologists’ Perspective from Bedside to Bench

Vestibular schwannoma is a medically benign schwannoma that arises from the vestibulocochlear nerve that causes sensorineural hearing loss. Therefore, an otologist's most difficult problem is preventing hearing loss due to the disease's natural course and surgical complications. The treatment of vestibular schwannomas has been lauded recently. These include advancements in intraoperative monitoring techniques for vestibular schwannoma surgery, where the likelihood of hearing loss as a result of a complication is minimized. A more accurate hearing prognosis will be achieved by precise genomic analysis of the tumor, which would aid in determining the characteristics of the disease for each patient. This report summarizes recent developments in vestibular schwannoma diagnosis and therapy, especially in hearing conservation. In addition, recent findings in the understanding of vestibular schwannomas' molecular mechanisms and how these advances can be used in clinical practice have been outlined and discussed.

Source link: https://doi.org/10.3390/diagnostics12051044

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions