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Last Updated: 20 May 2022

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Spatial Analysis for Mariculture Site Selection: A Case Study of Kukup Aquaculture Zones in the Peninsula of Malaysia

In the last five years, marine aquaculture sites in Kukup Strait, Malaysia's peninsula, have seen a decline in water quality, leading to increased mortality, seasonal massive fish mortalities, and poor profitability. Several site selection criteria are used in determining the proposed aquaculture industrial zone: 10 m to 30 m, 2 located within the Kukup port limits, and 4 kilometers from Kukup's mainland; 1 bathymetry depth operational requirement: 10 m to 30 m. Tropical finfish can survive under these conditions, with poorer fish health and higher fish mortality. A Moderate-intensity aquaculture system using HDPE cages may be profitable for the local fish farmers. Therefore, it is recommended that other Kukup Straits locations with deeper waters > 25 meters for potentially improved water quality and the ability for intensive aquaculture production be investigated for a greater depth and economics of scale.

Source link: https://doi.org/10.3389/fmars.2022.888662


Spectral induced polarization imaging to investigate an ice-rich mountain permafrost site in Switzerland

Measurement of polarization response of frozen rocks was obtained at the Lapires talus slope, a long-term permafrost monitoring station in the western Swiss Alps, to determine the possibility of the frequency dependence of the electrical polarization response of frozen rocks for an enhanced permafrost characterization. In ambiguous situations based on their innate spectral behavior, SIP results may help to distinguish ice-rich permafrost and unfrozen bedrock in ambiguous cases, with ice-rich permafrost and unfrozen bedrocks showing a stronger polarization toward higher frequencies in accord with the well-known spectral response to ice.

Source link: https://doi.org/10.5194/tc-16-1903-2022


Imatinib disassembles the regulatory core of Abelson kinase by binding to its ATP site and not by binding to its myristoyl pocket

Although imatinib's affinity for the allosteric web site is less than for the ATP site, imatinib bonding to the allosteric site may disassemble Abl's regulatory core, increasing kinase activity, particularly for Abl mutants with reduced imatinib ATP-site similarity. It was claimed that the previously observed imatinib-induced opening of the Abl regulatory core was due to imatinib binding to the allosteric site rather than the ATP site.

Source link: https://doi.org/10.5194/mr-3-91-2022


Whole‐room ultraviolet sanitization as a method for the site‐level treatment of Pseudogymnoascus destructans

P. destructans in the lab are identified as dead in the lab, and whole-room UV sanitization is a common procedure in numerous commercial settings. Before field testing, confirming that UV sanitizers can be used to treat hibernacula's complicated topography, as well as determining the effects of such topography on effective treatment times is essential. We use a laboratory setting to see if whole-room UV sanitization can be used to treat P. destructans' environmental reservoirs. We estimated treatment times for killing P. destructans in a natural environment from these results. Angles of emission and incidence increased to a maximum distance of 21. 3 meters; nevertheless, we find that UV sanitization can be a cost-effective, scalable, and relatively inexpensive method of lowering P. destructans populations in a 2 h.

Source link: https://doi.org/10.1111/csp2.623


Genome-wide analysis of methylation in rat fetal heart under hyperglycemia by methylation-dependent restriction site-associated DNA sequencing.

Diabetes mellitus has an elevated incidence of congenital heart malformations. Changes in methylation levels in the fetal heart of a rat model of hyperglycecemia was measured by MethylRAD sequencing in this research. Gene Ontology and Genomes analysis examined the genetic variations in methylation genes based on the CCGG and CCNGG websites in the upstream region. Gene Ontology reported that the CCGG-based DMGs involved in biological process and function were mostly connected to transcription and co-SMAD binding, with transcription and co-SMAD binding. According to the Kyoto Encyclopedia of Genes and Genomes review, CCGG-based DMGs were mainly involved in the Wnt signaling and TGF- signaling pathways. Both TNF signaling and apoptosis pathways were involved in the CCNGG-based DMGs. These genes may also be potential molecular targets or diagnostic biomarkers for heart malformations during hyperglycemia.

Source link: https://doi.org/10.1371/journal.pone.0268117


Identification of the potential active site of the septal peptidoglycan polymerase FtsW.

During bacterial cell growth and division, SEDS proteins are highly conserved peptidoglycan glycosyltransferases that construct complexes of class B penicillin-binding proteins that can synthesize PG during bacterial cell growth and division. However, how SEDS proteins recognize their substrate lipid II, the glycan layer's building block, and polymerize it into glycan strands is also unclear. Interestingly, the majority of the dominant-negative FtsW mutations are found in extracellular loops that are highly conserved in the SEDS family. We found that these mutations delayed septal PG synthesis but not affected FtsW localization to the division site, contact with its suppliers, nor substrate lipid II, which is consistent with this. We found that these mutations stopped septal PG synthesis but not affected FtsW localization to the division site, nor its substrate lipid II. Weakness aside from this, we found that these mutations prevented septal PG synthesis but not the substrate lipid II.

Source link: https://doi.org/10.1371/journal.pgen.1009993


Pig Management Strategies in the East Liao River Basin From the Bronze Age (c. 2000–256 BC) to the Liaojin Dynasties (907–1234 AD): Stable Isotope Analysis of Animals at the Changshan Site, Jilin Province, China

Pig domestication and management strategies have been increasingly discussed in recent years, emphasizing the temporal-spatial differences of pig management strategies. The East Liao River Basin, with diverse ecosystems, cultural exchanges, and collisions, plays a significant role in the cultural transformation, exchange, and integration processes between Northeast China and the Central Plains. However, no study or discussion has been given regarding the continued presence of domestic animal management programs in the East Liao River Basin for a long time. Pigs in captivity were mainly fed by millet-based foods in the West Liao River Basin and the middle reaches of the Yellow River valley, where millet farming was properly developed, according to a few studies.

Source link: https://doi.org/10.3389/feart.2022.883481


Cross-sectional analysis of risk factors for surgical site infection secondary to spinal internal fixation via the posterior approach

Through the posterior approach, this research was conducted to determine the risk factors related to surgical site infection secondary to spinal internal fixation. Patients were selected for inclusion in this cross-sectional study who had undergone spinal internal fixation via the posterior approach. Conclusions This report contains information on SSI secondary to spinal internal fixation by the posterior approach.

Source link: https://doi.org/10.1177/03000605221099254


Postoperative Surgical Site Infections in the Department of General Surgery of a Tertiary Care Centre: A Descriptive Cross-sectional Study

The Center for Disease Control and Prevention has classified surgical site infection as a wound infection that occurs within 30 days of an operation or within a year, and the infection is thought to be secondary to surgery. The aim of this research was to determine the presence of postoperative surgical site infections in the Department of General Surgery of a tertiary care center's Department of General Surgery. Methods: A descriptive cross-sectional research was conducted in the Department of General Surgery of a tertiary care center from August 1, 2020 to July 30, 2021 with ethical approval from the Institutional Review Committee. Conclusions: In our study, the prevalence of surgical site infection was higher in comparison to other similar studies done in similar settings.

Source link: https://doi.org/10.31729/jnma.7316


Downscaling of climate change scenarios for a high-resolution, site-specific assessment of drought stress risk for two viticultural regions with heterogeneous landscapes

A water balance model was created to evaluate potential impacts of climate change on grapevines' water supply capacity, evapotranspiration as a result of slope and position, and viticultural management practices. The model was based on soil maps, a digital elevation model, the European Union vineyard-register, observed weather reports, and forecast weather estimates simulated by regional climate models and downscaled by a stochastic weather generator, and fuelled by a stochastic weather generator. On the scale of individual vineyard plots, this enabled conducting a risk assessment of the drought stress occurrences in Germany's wine-producing areas Rheingau and Hessische Bergstraße. The risk of drought stress varied considerably between vineyard plots, but it could rise for steep-slope areas in the future.

Source link: https://doi.org/10.5194/esd-13-911-2022

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions