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Last Updated: 19 July 2022

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Application of Noncontact Laparoscopic High Ligation of the Hernia Sac of the Vas Deferens in Children with Indirect Inguinal Hernia.

The aim of this investigation is to determine the effectiveness of vaping deferens noncontact laparoscopic high ligation of the hernia sac in children with indirect inguinal hernia. Methods and Methods: The retrospective analysis of 146 male children with IIH treated in the Anhui Children's Hospital from January 2018 to June 2019 was reviewed retrospectively. The inner ring opening was sutured and closed with the vaping deferens noncontact suture, and 64 patients in the control group were sutured and closed using the intradermal suture. Conclusion: The noncontact laparoscopic high ligation of the hernia sac to close the inner ring opening has many benefits: the procedure is simple; the recovery time is shorter than the conventional one; and it is a safe, efficient, and cost-effective surgical technique.

Source link: https://doi.org/10.1089/lap.2022.0086


Assessment of the Intestinal Absorption of Higher Olefins by the Everted Gut Sac Model in Combination with In Silico New Approach Methodologies.

This study was designed to determine the absorption potential of higher olefins through the gut wall as the experimentally determined bioavailability, which would advance the read-across hypothesis and justification, reducing the need for toxic studies for all of the higher olefins. In the in vitro ever-to-small intestinal sac model and then ranked, the absorption potential of a series of higher olefins was determined. The reactivity of the double bond is more apparent in the reactivity simulation study than the number of carbon atoms. Both parameter descriptors are largely dependent on the number of carbon atoms and less on the position of the double bond in the lipophilicity and permeability tests. These new approach methodologies, which include data on any trends or breakpoints in intestinal uptake and a hazard matrix based on carbon number and location of the double bond, in conclusion.

Source link: https://doi.org/10.1021/acs.chemrestox.2c00089


A proteomic approach reveals biomineralization and immune response for mantle to pearl sac in the freshwater pearl mussel (Hyriopsis cumingii).

Pearl sacs are created by a complex chemical and biochemical reactions during pearl production. We use proteomics to identify differentially expressed proteins of the mantle and pearl sac, as well as the biomineralization and immune response of the pearl sac formation process in Hyriopsis cumingii. We obtained DEP profiles between the mantle and pearl sac using iTRAQ technology and bioinformatics analysis. 74 DEPs were discovered between the pearl sac and outer mantle, 112 DEPs between the pearl sac and inner mantle, and 124 DEPs between the outer and inner mantles, out of 74, 74 DEPs were discovered between the pearl sac and outer mantle, 112 DEPs between the pearl sac and inner mantle, and 124 DEPs between the pearl sac and inner mantle, with 112 DEPs between the pearl sac and inner mantle Our findings contribute to better understanding pearl formation and immune response, as well as future research into the production of high-quality freshwater pearls and the establishment of the freshwater pearl industry.

Source link: https://doi.org/10.1016/j.fsi.2022.06.057


Growth, osmoregulation and ionoregulation of longfin smelt (Spirinchus thaleichthys) yolk-sac larvae at different salinities.

Longfin smelt is a vulnerable anadromous fish species that reproduces in freshwater to moderately brackish areas of the upper San Francisco Estuary's upper San Francisco Estuary and has decreased to just 1% of its pre-1980s numbers. Despite 50+ years of population surveillance, the results of ten+ years of conservation efforts for longfin smelt have been largely unclear due to a lack of knowledge of how the species responds to environmental change, such as salinity. We investigated the effects of salinity on longfin smelt yolk-sac larvae here. According to our results, larvae grew largest and lived the longest when reared at 5 and 10 ppt, respectively, while yolk resorption stalled at 0. 4 ppt. Longfin smelt yolk-sac larvae likely perform best under moderately chilly conditions, yielding a mechanism that explains their distribution in field surveys and providing important information for future conservation efforts.

Source link: https://doi.org/10.1093/conphys/coac041


Canine Apocrine Gland Anal Sac Adenocarcinoma: A Review.

Apocrine gland anal sac adenocarcinoma is a relatively rare tumor in the dog and accounts for about 17% of perianal malignancies; however, it is one of the most common causes of paraneoplastic hypercalcemia. When present, the most common signs in affected dogs are attributed to mechanical blockage caused by the primary tumor or expanded regional metastatic lymph nodes, as well as paraneoplastic hypercalcemia. Most dogs' first treatment strategy, utilizing surgical excision and metastasectomy of the affected locoregional lymph nodes, is the most common first treatment approach, although radiation therapy and adjuvant chemotherapy are often integrated into multi-modality therapy regimens.

Source link: https://doi.org/10.1016/j.tcam.2022.100682


Transcriptome analysis of the ink sac and brain tissues from Sepiella inermis: A resource for discovering genes related to the inking of cephalopods.

The common Chinese cuttlefish is a valuable cephalopod with dietary and commercial value. However, the cellular basis for S. inermis' behaviour remain uncertain. In the present study, transcriptome analysis was performed on ink sac and brain tissue from S. inermis under two different conditions, i. e. To determine the global gene expression differences, the control group and the experimental group will determine the global gene expression differences. The differentially expressed genes in the ink sac and brain tissues were identified respectively, with 330,699 unigenes obtained from twelve transcriptome libraries via the Illumina Heeq X platform. Multiple genes in the ink sac were involved in cation transporter activity, according to several upregulated genes. The results from this research reveal an important transcriptomic resource for discovering key genes related to S. inermis' inking behavior, providing a basis for the development of alternative methods to shield S. inermis from intensive inking.

Source link: https://doi.org/10.1016/j.margen.2022.100968


Expression of genes associated with apoptosis in the residual yolk sac during the perihatch period of broiler chicks.

The yolk sac and the immediate YS tissue are mixed, providing essential nutrients and physiological functions for the developing embryo. The YS begins to decline after the YS is internalized into the embryonic chick's abdominal cavity. The YS tissue was collected from broiler chicks from embryonic d 17 to d 7 posthatch. Bcl2L11, cytochrome C, 3, 6, 8, 9, and 18 all showed a linear response from embryonic to d 7 posthatch. A DNA fragmentation assay was carried out to confirm the role of apoptosis in the YS tissue's degeneration. On the day of hatch, degradation of genomic DNA in the YS tissue began. The YS posthatch is degrading due to apoptosis, according to combined gene expression and DNA fragmentation findings.

Source link: https://doi.org/10.1016/j.psj.2022.101966


Brooding Temperature Alters Yolk Sac Absorption and Affected Ovarian Development in Goslings.

In order to determine the brooding temperature on yolk sac absorption and ovary growth of goslings, 126 1-day-old female goslings were randomly divided into three groups with three replicates in each group. The body weight of G29 and G26 was significantly higher than that of G32 at 72 h. At 2 weeks of age, the ovary index, ovary, and body weight were all significantly higher in G29 than those of G32 and G26. In G29, the number of primordial follicles, number of primary follicles, and diameter of primary follicles were significantly higher than those in G32 and G26 at 4 weeks of age. The expression of CHK1 and SMAD4 in G29 was significantly higher than in G32, and the expression of FGF12 and SMAD4 in G29 was significantly higher than in G32, as opposed to G32 at 2 and 4 weeks of age.

Source link: https://doi.org/10.3390/ani12121513


Post-pubertal ovarian yolk sac tumor with unusual follicular growth pattern, simulating struma ovarii.

Rare ovarian tumor neoplasms are rare ovarian neoplasms, with Yolk sac tumors previously identified as endodermal sinus tumors. The microfollicular pattern resembling thyroid tissue has not been identified. We present here a case of yolk sac tumor in a 39-y/o female, who was born with pelvic masses and a high serum Alpha-fetoprotein serum. The tumor cells were positive for Alpha-fetoprotein and Glypican-3, according to a study by On Immunohistochemistry. In a middle-aged woman, this case establishes a new histomorphologic pattern of yolk sac tumors. It's vital to know that yolk sac tumors have various histological signs and appearances.

Source link: https://doi.org/10.1007/s13691-022-00558-7

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions