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Rashes - Europe PMC

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Last Updated: 23 July 2022

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The high incidence and risk factors of levetiracetam and lacosamide-related skin rashes in glioma patients

The main side effect of seizure therapy in patients with glioma is antiseizure drug-induced skin rash. However, there are no studies comparing the incidence of skin rashes in patients with glioma, LEV and LCM. We compared the prevalence of ASD-associated skin rash among 353 patients with glioma and 125 patients with meningioma with LEV or LCM, who underwent surgery between 2017 and 2019 at our hospital, between 2017 and 2019. Patients with glioma had a higher risk of ASD-related skin rash than those with meningiomas. Patients with glioma were also higher than previously reported rates of 1-3% in patients with epilepsy. Our findings show that adjuvant therapy with radiotherapy and a history of drug allergy is closely associated with a high risk of ASD-related skin rashes in patients with LEV and LCM patients.

Source link: https://europepmc.org/article/PPR/PPR504857


Racial disparities in skin tone representation of dermatomyositis rashes: a systematic review.

This systemic review assesses skin tone representation in photographs of DM rashes in medical education literature. Methods An examination was conducted of 59 dermatology, 11 neurology, 10 neuromuscular, 7 rheumatology, 7 sept, and 6 internal medicine textbooks that were published between 2011 and 2021, as well as three online image databases that were accessible through an online medical school library. On the Massey and Martin Skin Tone Scale, Authors classified skin tone independently from 1 to ten. 58. 2% of textbook images in MMSCS 5-10 were in online databases, and 86% of textbook images were in dermatology textbooks. Conclusions Patients with lighter skin tones were included in a greater number of DM-related educational products than those with darker skin tones. Because of erroneous skin testing, it's impossible to properly assess skin involvement in DM, resulting in inadequate exclusion from clinical trials.

Source link: https://europepmc.org/article/MED/34718435

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions