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Our aim was to determine the possibility of complete, spontaneous, and medically indicated preterm birth in women with fibroids. We found the following studies comparing preterm birth in women with and without fibroids. The main results were total preterm birth 37, 34, 32, and 28 weeks of gestation, as well as spontaneous and medically indicated preterm birth. Preterm birth 37 weeks of gestation, there were 256,650 singleton deliveries: 12,309 with fibroids and 244,341 without fibroids out of 37 weeks of gestation. Preterm birth was at a higher risk among women with fibroids. Fibroids were also associated with premature birth 34, 32, and 28 weeks of gestation. There were no studies regarding preterm birth or premature birth of fibroids, and another with reported preterm birth. By systematic myometrial examination in pregnancy, we can better determine the connection between fibroids and preterm birth.
Source link: https://doi.org/10.1371/journal.pone.0269478
Background Spontaneous preterm birth is a leading cause of neonatal morbidity and mortality in the world, and determining its risk factors is vital to reduce its prevalence. There are no studies examining this issue, however, it is hypothesized that vaping hygiene habits can change the vaginal microbiome and are therefore associated with SPTB. We compared 79 women with a SPTB to 156 women with a term birth for a total of 79 women. All participants completed a questionnaire regarding vaginal washing with water, soap or gel, the use of intravaginal douches, and vaginal steaming, both before and during pregnancy. SPTB was linked to the use of vaginal gel prior to pregnancy and even more during pregnancy, according to the authors. Conclusions Our results show that the use of vaginal gel is associated with SPTB. Women should be warned that vaping gels used for vaping may not be safe.
Source link: https://doi.org/10.1371/journal.pone.0268248
Background Preterm birth remains the most common cause of neonatal mortality, with morbidity being one of the key targets of neonatal health care. Ethiopia is one of the world's top preterm birth burdens. This research was therefore designed to investigate the causes of preterm birth in public hospitals in Sidama, California's southern state. Methods Facility-Based Case-Control Study At public hospitals in Sidama's Sidama regional state, from 1st June to 1st September/2020, a grant-based case-control investigation was conducted. P-value 0. 25 in the bivariate logistic regression were tested for multivariable logistic regression analysis. Conclusion The majority of the risk factors of preterm birth were found to be adaptable. Early detection of risk factors may help prevent preterm birth by community mobilization during pregnancy and antenatal care follow-up. In addition, preterm birth prevention information regarding information exchange was also suggested.
Source link: https://doi.org/10.1371/journal.pone.0265594
Results: The prevalence of preterm birth, low birthweight, and macrosomia in the study population was 5. 7 percent, 2. 8 percent, and 7. 1 percent, respectively. PTB risk was elevated in comparison to normal FF, according to low FF. Conclusion: Our report reveals that low FF at NIPS with PTB was significantly higher than those with normal FF and body mass index 25 at NIPS.
B Streptococcus is an opportunistic pathogenic bacterium that on colonization in the female reproductive tract can cause preterm births, fetal injury, and demise. However, the absence of one of the pathogens from the pathogen reduces one of the pathogenesis of GBS in terms of determinant preterm birth but does not fully eliminate the pathogenesis of GBS. This leads to a deeper look into the mechanistic basis of GBS-mediated preterm births as a result of further investigation into other virulence factors of GBS pathogenesis.
Source link: https://doi.org/https://doi.org/10.1530/RAF-21-0105
The studies investigating the relationship between anti-inflammatory factors IL-4 and IL-10 gene polymorphisms and PTB revealed conflicting results. In 21 studies, anthropomorphisms in two interleukins were discovered in 21 articles. The Eggers' publication bias plot was used to graphically represent the publication bias. ttb, IL-10-1082A/G and PTB were found in a significant association between IL-10-1082A/G and PTB, only the over-dominant gene model AA + GG vs. AG. In subgroup results by racial or control group Hardy-Weinberg Equilibrium p-value, no statistically significant correlation was found between IL-590C/T, IL-1095A/C, IL-10-819T/C, and IL-10-1082A/G polymorphisms and PTB. Conclusion The funnel asymmetry may be due to publication bias rather than heterogeneity in Eggers' publication bias plot and heterogeneity tests of IL-10-1082A/G revealed that the funnel asymmetry may be due to publication bias rather than heterogeneity.
Source link: https://doi.org/10.3389/fimmu.2022.917383
According to specific placental histological regions, the aim of this research was to determine differences in gene expression profiles in fetal monocytes u2014 cells that persist and differ postnatally. We found that fetal monocytes exposed to acute placental inflammation upregulate biological pathways related to monocyte mobilisation, monocyte chemotaxis, and platelet function, while monocytes exposed to maternal vascular malperfusion lesions downregulate these processes. Unique changes in fetal monocytes and monocyte subsets are shown by this first study to our knowledge, revealing that placental lesions are related to peculiar changes in fetal monocytes and monocyte subsets.
As an alternative to smoking, pregnant women may consider e-cigarettes during pregnancy. We created exposure categories based on self-reported number of cigarettes used per day and vaping frequency, as well as their correlations with preterm birth and small-for-gestational age birth based on self-reported number of cigarettes smoked per day and vaping frequency, determining their correlations with preterm birth and small-for-gestational-age birth. While dual users who heavy smoked and occasionally vaping had the highest adjusted OR for SGA, both the dual users had, on average, about twice the chance of having SGA than non-users. Although the risks of preterm birth were higher among sole light smokers and sole heavy smokers than non-users, the adjusted odds of preterm birth for dual users were not significantly different than those for non-users. Conclusion: Both smoking and vaping during pregnancy increase the risk of SGA, according to the researchers, but the increased risk of preterm birth seems to be largely due to smoking alone.
Source link: https://doi.org/10.1016/j.gloepi.2022.100079
paraphrasedoutput:Methods is a website that publishes articles aboutHow fertility causes and assisted reproductive technology therapy influence perinatal outcomes, and clarify the connection between the maternal pathophysiological changes and invasive interventions. According to the researcher, 1,629 fertile women and 27,112 infertile women with sole infertility causes were prospectively recruited from July 2014 to December 2017, with 9,894 singletons being accepted. On the effect of female infertility on GA women, an interaction test showed that ART treatment had an effect on female infertility. Compared to the fertile NC group, the female factor ART group had a higher risk of PTB and LGA than the fertile NC group. Conclusion ART and tubal factor ART were both elevated for LGA. Conclusion:Our results showed that ART therapy could amplify the adverse effect of female infertility on neonates.
Source link: https://doi.org/10.3389/fendo.2022.791229
Abstract An increase of cardiovascular and metabolic risk factors from childhood to middle age is shown by preterm birth with very low birth weight. We did magnetic resonance imaging on 78 adults born preterm at VLBW in Finland between 1978 and 1990, as controls, with a median age of 29 years. When adjusting for age, sex, and maternal and perinatal characteristics, the adipose tissue volumes of VLBW adults did not differ from their term peers. The mean differences were as follows: subcutaneous u2212 0. 4 percent, visceral 7. 96%, and total abdominal fat percentage 0. 55 percent. VLBW volunteers had less anxiety in subcutaneous adipose tissue but not so much in tibial bone marrow. Adult VLBW adults had similar adipose tissue volume and hepatic triglyceride content as their term siblings, with identical adipose tissue volume and hepatic triglyceride content.
Source link: https://doi.org/10.1038/s41598-022-13936-1
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