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If your children are at risk, the RetCam examination will be administered to identify retinopathy of prematurity in the neonatology department of the University Hospital of Grenoble and for those who are at risk. It will be a matter of filming the facial features of the child for 15 seconds before the exam and then filming the face of the child for 15 seconds at two separate times. A percentage of time on these 30 seconds has been found modified, as a result of heart rate and oxygen saturation testing, as well as a determination of heart rate and oxygen saturation.
Source link: https://clinicaltrials.gov/ct2/show/NCT04092127
The primary aim of the study: The main aim of the study is to determine the effects of music practice and Marmet Technique on lactation and maternal fear in mothers with premature babies. Hypotheses: H0: There is no difference in the amount of breast milk between the music, Marmet Technique, and control groups in mothers with premature babies in the neonatal intensive care unit. H1: There is a difference in the amount of breast milk produced by the music, Marmet Technique, and control groups in mothers with premature babies in the neonatal intensive care unit. There is no difference in maternal fear between music, Marmet Technique, and control groups in mothers with premature babies in the neonatal intensive care unit. H1: There is a difference in maternal fear among musicians, Marmet Technique, and control groups in mothers with premature babies in the neonatal intensive care unit. The effect size was determined using the G*Power 3. 1. 9. 2 software, and the mean, standard deviation, and sample size values of the breast milk variable included in the related article were factored in calculation of the effect size. Randomization: The mother's number will be in is determined by the random number generation website "Random Lists": the group that the mothers will be in is determined by the random number generation website "Random Lists": the mother's name is determined by the random number generation website. The level of anxiety rises as the scores rise, and 20 is rated as the lowest level of anxiety and 80 as the highest level of anxiety. "Random Lists" means that the mothers in Then, which is where the children will be divided into three groups as music, Marmet Technique, and control group. Since the mothers suffered on the post-op day 0 of pregnancy, it is expected to begin the research at 11:00 on the post-op 1st day. The data will be filled by the researcher who works as a midwife in the Neonatal Intensive Care Unit in the same hospital by face-to-face interview method in the Neonatal Intensive Care Unit's Breastfeeding Room. First and foremost, the State Anxiety Scale for the music group will be filled by the mother, and then the performance will be played for 15 minutes. It will be expected that the mother fills in the State Anxiety Scale again after the milking process. The State Anxiety Scale will be filled by the mother first, and massage and milking will be carried out for 20-30 minutes in accordance with the procedure's protocol. The mother will have to fill in the State Anxiety Scale once more after the milking process. Applications and milking process will be carried out separately by each group, 8 times in total, for both groups, st day 2 times, st day 2 times, st day 2 times, st day 2 times, st day 2 times, st day 2 times, st day 2 times, st day 2 times, st day 2 times, st day 2 times, st day 2 times, st day 2 times,.
Source link: https://clinicaltrials.gov/ct2/show/NCT05211076
The relationship between IVH and head positioning of the infants with low birth weight babies has made its way into academic studies, showing that venous obstruction can arise from increased external pressure on the venous system when the micro-preemie infant has their head elevated rather than holding their head positioned to the side rather than holding a neutral position. The investigators expect that using early consistent neutral positioning in contrast to the Neonatal Intensive Care Unit's standard care may reduce the risk of intraventricular hemorrhage in pregnant infants born in the United States from 306/7 weeks, which may have a positive effect on the incidence and/or severity of intraventricular hemorrhage in this population.
Source link: https://clinicaltrials.gov/ct2/show/NCT03543046
Although musical studies in premature infants are limited, a 2014 study published in Pediatrics showed how music-specific and the maternal voice can positively influence the behavior and neural responses of the preterm baby. On the other hand, reproduction studies in premature infants may have failed to investigate premature infants. Neonates with intraventricular hemorrhage and periventricular leukomalacia can also be enrolled. Both parents and the music therapist's reproduction of lullabies sung by both parents or by the music therapist might help with the acquisition of nutritional skills and the growth of the preterm infant. Investigating how this can influence the newborn's clinical stability is a key and primary point to investigate in order to be able to make the most of positive reinforcement's use. The purpose of this research is therefore to determine the acceptability of a receptive music therapy intervention by the enrolled infants and to investigate any benefits of positive reinforcement that has been used to increase nutrition and growth skills of preterm babies. Vital results: determining Heart Rate Variability u2022 (u2022) The primary aim of this research is to assess and monitor infant response to receptive music therapy, as part of music therapy therapy. Secondary results: positive reinforcement has had an effect on the acquisition of food skills and the growth of preterm infants.
Source link: https://clinicaltrials.gov/ct2/show/NCT04759170
In a placebo-controlled, double-blind research, the aim of this study was to determine the safety and effectiveness of intravenous cetamol in pain medication for small preterm infants. The primary result of the pain medication arm is the shortage of morphine tablets. Aim: To determine in a controlled, double-blind trial, the early onset of the painkiller treatment of a preterm infant. Aim: to investigate the pharmacokinetics and pharmacokinetics of cotamol in a preterm infants Aim: To determine the long-term consequences of the early, intravenous chemotherapeutic drug acetateamol in preterm infants needing intensive care. 3 Sample size: After the first randomization, the sample size for the pain medication trial was tested. Patients and exclusion criteria for this research will be recruited from all the intubated premature babies born in Oulu University Hospital's neonatal intensive care unit, regardless of their gestational age. Blinding and 5 randomization: As the informed consent is obtained, the study patient receives a trial number from the list published prior to the study's enrollment. The study may be prepared by the study nurse or by a nurse who does not participate in the study patients' treatment in any way. After the last dose of study drugs, there should be at least two days absence of paracetamol therapy if the patient's medical condition necessitates starting of paracetamol therapy. About 4. 5 hours, a half-life of intravenous ketamol in neonates is about half-life. 6. 1 Monitoring of the pain: The pain or discomfort of the patients will be assessed using NIAPAS scoring before and after the study drug administration will be determined. According to the NIAPAS' NIAPAS recommendations, values > 5 indicate the need for pain relief, whether using the non-medical pain relief products or increasing the pain medication dose. Whether it be morphine ad 0. 1 mg/kg single doses or morphine infusion, all of the study participants will receive the correct painkillers during the study, whether it be morphine ad 0. 1 mg/kg single doses or morphine infusion. No one of the preterm infants who received telamol showed any clinical or laboratory signs of either complication in the latest retrospective review of the study unit patient population. The liver intoxication of inequalation with paracetamol is caused by a phenolic metabolite rather than paracetamol itself. The hepatic tissue damage can be prevented from administering the ketamol antidote as soon as possible. Early acetyl cysteine therapy can reduce the hepatic failure, but even when started later, the tissue damage can be limited. 8 Monitoring, and follow-up of the potential side effects: All of the study patients will be monitored for signs of potential side effects, particularly those of hepatic or renal dysfunction. 9 Pharmacokinetics: From those study patients with an arterial cannula, a single 1 ml blood sample at 48 hours postnatal age will be collected to determine cetamol serum concentrations and prematurity's biological effects. The study findings will be collected using Centricity Critical Care Clinisoft software, and the 10 Data sets will be gathered: The study findings will be collected and stored using Centricity Vital Care Clinisoft software. Patients will be analyzed for the medical history, basic laboratory findings, and, if necessary, radiographic studies.
Source link: https://clinicaltrials.gov/ct2/show/NCT01938261
In childhood, preterm infants have elevated numbers of viral infections. Although studies have shown that premature infants have reduced adaptive and innate immune responses in comparison to infants born at term, no research has been done into whether this impaired immunity improves and becomes similar to full term infants after the ex-preterm infants reach term-corrected gestational age. Given the preterm immune system's immunity and the numerous potential infectious and inflammatory insults they are exposed to during the preterm period, there is also a chance that preterm infants' relative immunodeficiency may persist into infancy. In preterm and former preterm infants, the present study will investigate the origins and function of T and B cell compartments.
Source link: https://clinicaltrials.gov/ct2/show/NCT03433846
Hypothesis1: The first demonstrators in the UCM family are not inferior to the DCC group. Hypothesis2: If H1 is correct, show a reduced risk of severe IVH and/or death in UCM infants relative to DCC. Hypothesis3: With no differences in bilirubin or polycythemia, the UCM group will have a reduced need for resuscitation procedures, as opposed to DCC. Hypothesis4: UCM has improved blood pressures in the first 24 hours of life in comparison to DCC.
Source link: https://clinicaltrials.gov/ct2/show/NCT03019367
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