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Post-Traumatic Stress Disorder - U.S. Department of Veterans Affairs

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Last Updated: 12 June 2022

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Prevalence, Severity and Burden of Post-Traumatic Stress Disorder in Black Men and Women Across the Adult Life span.

"We found PTSD persistence and severity by age group," she said, followed by comparisons of PTSD with socioeconomic status, chronic anxiety, and racial discrimination in middle-age. PTSD was also higher in Black women/men between 18-34 and 35-49, compared to 50 and older. PTSD was linked to jobs, lower education, poverty, and violence among Black men, as well as unemployment, lower education, hunger, and poverty in Black men, as well as racism, violence, poverty, and discrimination against Black women in middle-age. Essay on middle Age: Black women live with a disproportionate burden of PTSD in middle age. ".

Source link: https://doi.org/10.1177/08982643221086071


Worse sleep, worsening post-traumatic stress disorder (PTSD): Poor sleep quality associated with increases in PTSD symptoms amongst those experiencing high threat of the COVID-19 pandemic.

"The present review investigated the relationships of self-reported sleep quality and anticipation risk appraisals of the pandemic with PTSD symptoms six months later in a population enriched for pre-pandemic trauma exposure and PTSD. " At a follow-up measuring baseline PTSD symptoms, baseline sleep quality was associated with PTSD symptoms. The pandemic risk was moderated by this association, with worse sleep quality attributed to more frequent PTSD symptoms at a follow-up for participants with a higher but not lower threat of the COVID-19 pandemic. These results show that inadequate sleep quality may contribute to later PTSD during the pandemic, particularly among those individuals who think the pandemic is threatening to their health. Sleep-related disorders may be helpful for reducing trauma-related symptoms during and after the global health crisis. ".

Source link: https://doi.org/10.1111/jsr.13568


Evidence for excess familial clustering of Post Traumatic Stress Disorder in the US Veterans Genealogy resource.

"Analysis of familial clustering among VHA patients with Post Traumatic Stress Disorder provided the opportunity to investigate the possibility of an inherited link to PTSD. " Patients with genealogy information with PTSD were identified by the presence of an ICD diagnosis code in the VHA medical record in at least two years. Patients with PTSD were diagnosed with PTSD and their expected similarity to their predicted average similarity with their estimated average relatedness, determined from randomly selected sets of matched linked VHA patient data. According to all linked VHA patients, PTSD prevalence was estimated in first-, second-, and third-degree relatives of PTSD patients who were also VHA patients. These findings support an inherited contribution to PTSD predisposition and reveal a valuable source of high-risk PTSD pedigrees for predisposition gene identification.

Source link: https://doi.org/10.1016/j.jpsychires.2021.12.018


C-Reactive Protein: Marker of risk for post-traumatic stress disorder and its potential for a mechanistic role in trauma response and recovery.

"Inflammation has been documented in chronic stressors, promoting persistent avoidance and arousal behaviours after severe stressors," "Rodent studies show that inflammation promotes continuing avoidance and arousal responses. " It's also shown that inflammation plays a mechanistic role in trauma disorders. " CRP gene mutations, elevated peripheral CRP, CRP gene mutations, and CRP gene expression changes in immune signaling pathways are among the growing number of studies that have investigated connections with PTSD diagnosis and elevated peripheral CRP, CRP gene mutations, and CRP gene mutations in immune signaling pathways. We discuss the current understanding of immune mechanisms in PTSD in this report, with a particular emphasis on the innate immune signaling component, CRP. Although CRP is linked to PTSD symptoms and risk, there is a paucity of evidence on how CRP might exacerbate PTSD inflammation and PTSD, as well as PTSD symptoms and risk, which has exacerbated PTSD symptoms and risk, as well as PTSD symptoms and risk, we discovered. We explore how CRP could influence enduring peripheral and CNS stress responses, as well as future areas of study into the role of CRP and other common immune signaling factors in modulating trauma responses.

Source link: https://doi.org/10.1111/ejn.15031

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions