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Position Effect - PubMed

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Last Updated: 17 January 2023

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Effect of alanine versus serine at position 88 of human transthyretin mutants on the protein stability.

Human TTR stability has been investigated by using thermodynamic simulations based on all-atom molecular dynamics simulations to determine the effects of the His88 u2192 Ala and Ser mutations. The H88A mutant is more stable than the wild type, according to simulation results, while the H88S mutant is less stable than the wild variety. According to a quantitative analysis of the free energy change difference between the He88 u2192 Ala and His88 u2192 Ser mutations mainly resulted from electrostatic and van der Waals interactions, respectively. The H88A mutant is more robust than the wild variety, although van der Waals interaction destabilizes the H88S mutant relative to the wild variety. Mutant mutants with individual residues contribute to the free energy transition show that neighboring residues have a deterministic and destabilizing presence.

Source link: https://doi.org/10.1093/protein/gzad001


Effect of hologram plane position on particle tracking using digital holographic microscopy.

Using digital hologram microscopy, this paper explores the effect of hologram plane position on particle tracking in a 3D suspension using digital hologram microscopy. We compare two optical designs in which the hologram plane is either directly outside the particle suspension or in the middle of the suspension. Compared to the other, we find that the optical setup in which the hologram plane is embedded in the middle of the sample provides superior tracking results, including higher precision in particle displacement measurements and longer particle trajectories.

Source link: https://doi.org/10.1364/AO.473763


The Influence of Contextual Factors on the Relative Age Effect in Male International Rugby Union: The Impact of Sociocultural Influences and Playing Position.

The aim of this report is not only to determine whether the relative age effect exists in male international rugby union players, but also to investigate sociocultural influences and playing position. From the top ten nations of the World Rugby rankings, the birth date and playing position of 7144 senior male professional rugby players included in the rosters of the season 2020-2021 were determined. Despite a more noticeable RAE emerging for southern players, the RAE was poor in players competing in both hemispheres.

Source link: https://doi.org/10.3390/children9121941


The Effect of Trunk Position on Attentional Disengagement in Unilateral Spatial Neglect.

The following three patients with early stroke onset were classified as follows: USN, right brain injury without USN, and left brain damage were all reported. The MPT was affected by a situation in which the preceding cue and target direction were the same, as well as a case in which the directions were opposite. In the invalid left situation, the trunk right condition's RT was dramatically reduced relative to that of trunk midline and left conditions. This report aids in the recovery of patients with neglect symptoms.

Source link: https://doi.org/10.3390/neurolint14040083


The co-effect of sensate focus technique and sexual position changing on sexual function of women who use medical treatment for endometriosis.

This study was designed to investigate the effects of sensate focus technique and sexual position shifting on the sexual characteristics of women who used medical therapy for endometriosis. The mean score of sexual function in the intervention group had significantly improved eight weeks after the intervention, according to a few weeks before the intervention. In the follow-up periods in the intervention group, the mean score of sexual pain was significantly different than that before the intervention and control groups were established. Several research have discussed the role of endometriosis in the emergence of sexual dysfunction in women. These results have a positive effect on sexual function and dyspareunia in women with endometriosis undergoing medical intervention to improve their sexual health, as well as more research.

Source link: https://doi.org/10.1080/01443615.2022.2158316


Effect of Nasogastric Tube Placement, Manipulation, and Fluid Administration on Transcutaneous Ultrasound Visualization and Assessment of Stomach Position in Healthy Unfed and Fed Horses.

Given the variability in time since feeding and the common use of nasogastric tubes in horses with colic, the interpretation of gastric ultrasound in horses with colic necessible. In ten unfed horses and five fed horses, before and after the introduction of 6 L of water in unfed horses, Cranial to caudal and dorsal to ventral ultrasonographic dimensions were determined, before and after nasogastric tube placement. In horses that have recently fed and/or had a nasogastric tube installed, the increase in gastric ultrasound dimensions can have occurred without pathologic gastric distension related to colic, and should be treated in this context. Equine reflux is likely to be more frequent than standard ultrasound measurements of gastric dimensions to identify horses with colic likely to have significant gastric reflux.

Source link: https://doi.org/10.3390/ani12233433

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions