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Placebo - BioProject

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Last Updated: 26 September 2022

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ROSCO-CF is an exploratory, phase 2a, randomized, double-blind, placebo-controlled, parallel-group study conducted to assess the safety and efficacy of oral R-roscovitine in chronic Pseudomonas aeruginosa (PA) lung infections in patients with cystic fibrosis (pwCF).

Shortly, the ROSCO-CF research was a safety validation, double-blind, placebo-controlled, dose-ranging study, phase IIa clinical trial in France on 34 CF patients chronically infected with PA and with at least one F508del-CFTR mutation.

Source link: https://www.ncbi.nlm.nih.gov/bioproject/875754


Effects of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 on Overweight and Gut Microbiota in Human: Randomized, Double-Blinded, Placebo-Controlled Clinical Trial

Obesity and obesity are closely linked to diet, and gut microbiota play a key role in body weight and human health. The aim of this review was to determine how Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 supplementation may have reduced obesity by modifying the human gut microbiome. Probiotic groups in HY7601 and KY1032, for example, consumed 5109 colony-forming units of HY7601 and KY1032, over a 12-week period, while the placebo group consumed the same product without probiotics. In addition, HY7601 and KY1032 supplementation improved bacterial gut microbiota characteristics and beta diversity by increasing Bifidobacteriaceae and Akkermansiaceae, as well as decreasing Prevotellaceae and Selenomonadaceae.

Source link: https://www.ncbi.nlm.nih.gov/bioproject/836304


Microbial analysis of patients with diagnosed depression after treatment with Probiotics and Placebo.

The u201d, the producer of the drug, was Winclove BV, and the placebo included sampling of fasting blood, stool, socioeconomic, and cognitive assessment as well as a medical interview discussing side effects of drugs and clinical signs. OMNi-BiOTiCu00ae Stress Repair is a commercial dietary supplement that contains nine bacterial strains with at least 7. 5 billion organisms per 1 portion. Bifidobacterium lactis W52, Bifidobacterium lactis W51, Bifidobacterium lactis W51, Bifidobacterium lactis W51, Lactobacillus casei W52, Lactobacillus plantarum W22, Lactobacillus plantae W21, Lactobacillus plantarum W21, Lactobacillus lactis W21, Bifi W21, Bifi W21, Bifi W53, Bifi W51, Bifi W52, Bifi B21, Bifi W51, Bifi W51, Bifi W52, B21, Bifi W20, Lactis W52, Bifi W51, Lactis W21, Bifi W52, Lactis W52, BifiCu201Dae Lactobacillus & W53, BifiCu201d In addition, 125 mg D-Biotin, 30 mg of common horsetail, 30 mg of fish collagen, 30 mg of fish collagen, and 30 mg of keratin plus matrix were added to the probiotic formulation.

Source link: https://www.ncbi.nlm.nih.gov/bioproject/794491


Human OA cartilages treated with ANGPTL3 mimetic LNA043 and placebo

In this research, the raw data are not available for patient confidentiality reasons because of the patient's treatment with placebo and LNA043; each from 7 and 9 patients treated with placebo and LNA043 was used, according to the researcher.

Source link: https://www.ncbi.nlm.nih.gov/bioproject/773037

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions