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Peripheral Neuropathy - Wiley Online Library

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Last Updated: 15 July 2022

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First‐in‐Human Single‐Ascending‐Dose, Multiple‐Dose, and Food Interaction Studies of NRD.E1, an Innovative Nonopioid Therapy for Painful Diabetic Peripheral Neuropathy

Painful diabetic peripheral neuropathy is characterized by spitting, stabbing, or electric shock (u2013type pain), which severely affects day's functioning and quality of life. Healthy male subjects received 300 mg of NRD. E1 every day for five days for five days during the second research, which was a placebo-controlled multiple-u2010dose experiment. Following a crossover study, NRD. E1 was administered under fed and fasted conditions at 40 mg, according to the third research, which was an open-u2010label food interaction study in healthy men and women.

Source link: https://onlinelibrary.wiley.com/doi/10.1002/cpdd.1103

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions