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Systemic lupus erythematosus is a chronic illness that causes inflammation in connective tissue, such as cartilage and blood vessels, which give strength and flexibility to structures throughout the body. SLE is one of a large group of disorders classified as autoimmune disorders that arise when the immune system attacks the body's own tissues and organs. Joint pain, generally affecting both sides of the body, joint pain, muscle pain, and weakness are all common problems that affect people. In SLE, skin issues are common. Calcium deposits under the skin, damaged blood vessels in the skin, and tiny red spots called petechiae are among the skin conditions that may develop in SLE. Individuals affected by the moist lining of the mouth, nose, or, less often, the genitals may suffer hair loss and open sores. About a quarter of people with SLE have kidney disease, according to a spokesperson. Heart disease can also occur in SLE, including inflammation of the sac-like membrane around the heart and abnormalities of the heart valves, which regulate blood flow in the heart. Heart disease caused by fatty buildup in the blood vessels, which is extremely common in the general population, is even more prevalent in people with SLE. Anxiety and depression are also common in SLE. People with SLE have episodes in which the disease gets worse and then get better, while others with better health have episodes.
Myhre syndrome is a rare disorder that affects connective tissue. The first signs of Myhre syndrome include narrow openings of the eyelids, deeply set eyes, a short distance between the nose and upper lip, a narrow upper lip, and a protruding lower jaw. Children with Myhre syndrome have delayed growth, which is evident by age 5, which is apparent by age 5. People with Myhre syndrome have behavioral disorders similar to those with autism spectrum disorders, which affects communication and social interaction. Most people with Myhre syndrome have hearing loss, often beginning in childhood and gradually worsening. Following injury or illness, Fibrosis in Myhre syndrome can occur in the absence of injury or injury after surgery or trauma. Individuals with Myhre syndrome have a tendency to have heart abnormalities that are not present at birth. High blood pressure and narrowing of the heart valves or blood vessels can lead to further problems, such as elevated blood pressure and narrowing of the heart valves or blood vessels. Abnormalities of the lungs and airways in people with Myhre syndrome include narrowing of the windpipe and the passages leading from the windpipe to the lungs; difficulty filling the lungs with air when inhaling; or widespread lung damage. People with Myhre syndrome may also be at risk of developing cancerous or noncancerous tumors, including tumors of the uterus lining.
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