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Selective serotonin reuptake inhibitors are a newer class of antidepressants that might have certain effectiveness in Parkinson's disease offered the recognized serotonergic changes in this disease. Several current case reports, nevertheless, have raised problem that SSRIs may worsen parkinsonian motor function. We checked 71 Parkinson Study Group private investigators making use of a standard survey regarding their use of antidepressants in PD. Based on price quotes provided by 49 private investigators who reacted, 26% of patients with PD get on pharmacotherapy for anxiety. These doctors use SSRIs as first line treatment 51% of the time, tricyclic antidepressants 41% of the moment and other agents 8% of the time. Our survey validates that for treating medical professionals there stay uncertainties pertaining to the relative efficacy and tolerability of available antidepressant medications for patients with PD.
Source link: https://doi.org/10.1212/wnl.49.4.1168
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