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Parenteral Nutrition - Springer Nature

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Last Updated: 27 July 2022

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Calculation and management of ketogenic diet parenteral nutrition in super-refractory status epilepticus

Ketogenic diet parenteral nutrition is ketogenic diet therapy delivered by parenteral administration, and it may be an adjuvant treatment for those who are unable to tolerate enteral diet. This report examines the practical aspects of KD-PN therapy for treating SRSE, including diet, potential drug-diet interactions, and monitoring during KD-PN therapy. Propofol infusion syndrome is one of many adverse effects that can be related to SRSE treatments, such as hyperlipemia, renal acidosis, inadequate ketosis, or hyperketosis.

Source link: https://doi.org/10.1186/s42494-022-00095-z


Offering Guidance and Learning to Prescribers to Initiate Parenteral Nutrition using a Validated Electronic Decision TREE (OLIVE TREE)

Pediatricians who are nutritionally fragile and unable to receive oral or enteral nutrition are urged to receive parenteral nutrition. A standardized electronic PN order structure could help with more effective PN prescribing. The OLIVE TREE consists of 120 individual items. To determine interrater agreement between a pharmacist and the treating physician, a process validation was carried out. A proof of concept analysis was conducted to determine the number of patients for whom the OLIVE TREE had an active and potentially beneficial effect on physicians' prescribing behavior. The number of patients for whom PN was approved and the percentage of decisions not in accordance with the recommendation were also estimated. The process validation of 20 patients resulted in a 95 percent interrater agreement. In 53 percent and 79. 5% of these patients, respectively, the proof of concept in 73 patients resulted in an effective and potential influence on prescribing behavior. Our newly produced OLIVE TREE has a good process stability, which makes it a good selection choice.

Source link: https://doi.org/10.1007/s10916-022-01835-x


Fish oil-containing lipid emulsions prevention on parenteral nutrition-associated cholestasis in very low birth weight infants: a meta-analysis

Background information is uncertain about the effect of fish oil-containing lipid emulsions on preventing parenteral nutrition-associated cholestasis in infants under very low birth weight. Methods PubMed, EMBASE, and CENTRAL were among the sources of scholarly research relating to the preventive effect of fish oil-containing lipid emulsions and fish oil-free lipid emulsions in VLBW infants studying cholestasis. Emulsion containing fish oil reduced the incidence of PNAC by a large margin, 0. 3 percent confidence interval 0. 36-0. 90, P = 0. 002. Conclusions: Based on the existing original randomized controlled trial studies, the fish oil-containing lipid emulsion can minimize the incidence of PNAC in VLBW infants, especially in patients with parenteral nutrition durations exceeding 14 days and extremely low birth weight infants.

Source link: https://doi.org/10.1007/s12519-022-00536-2


Co-administration of drugs with parenteral nutrition in the neonatal intensive care unit—physical compatibility between three components

The purpose of this investigation was to obtain verified physical compatibility data for intravenous therapy to neonatal intensive care unit patients, but there is a lack of compatibility data for intravenous therapy. Potential droplet growth and emulsion destabilization was assessed by estimating PFAT5 from droplet size measurements and numbers, mean droplet diameter and polydispersity index from dynamic light scattering, and pH measurements. As a result of mixing and testing, mixed samples were always compared to unmixed controls to detect changes as a result of mixing and sampling, and after 4 h to simulate long contact time. Dopamine, morphine, and cefotaxime were found to be compatible with NumetaG13E, and it's safe to co-administer these drugs with this PN in NICU patients. u2022 - the co-administration of Numeta G13E with dopamine and morphine, but also with morphine and cefotaxime is safe in NICU.

Source link: https://doi.org/10.1007/s00431-022-04466-z


Effect of Short-Term Preoperative Parenteral Nutrition Support for Gastric Cancer Patients with Sarcopenia: a Propensity Score Matching Analysis

Introduction Sarcopenia is well known as unfavorable prognostic marker for gastric cancer patients. This review was designed to determine the efficacy of short-term preoperative parenteral nutrition in GC patients with sarcopenia. Methods and Methods We collected data on GC patients with sarcopenia who underwent radical gastrectomy at our hospital from 2010 to 2018. Results In total, 428 patients met the inclusion criteria, and propensity scores identified 166 matched pairs of patients with sarcopenia. The PN group had a lower incidence of intra-abdominal disease and higher hospitalization costs than the control group. In addition, a subgroup review revealed that short-term preoperative PN support is associated with reduced postoperative surgical complications in patients with albumin levels below 35 g/L. Conclusions Short-Term preoperative PN assistance is not associated with reduced overall complication risk in patients with GC and sarcopenia.

Source link: https://doi.org/10.1007/s11605-021-05185-w

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions