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Polycystic kidney disease is a disease that affects the kidneys and other organs. Risk factors of polycystic kidney disease include dangerously elevated blood pressure, pain in the back or sides, blood in the urine, recurrent urinary tract infections, kidney stones, and heart valve abnormalities. In addition, people with polycystic kidney disease are at a greater risk of an abnormal bulging in a large blood vessel called the aorta or in blood vessels at the base of the brain. The two main types of polycystic kidney disease are distinguished by their age of onset and the pattern in which it is passed through families. Depending on the genetic cause, autosomal dominant polycystic kidney disease can be further divided into type 1 and type 2 according to the patient's genetic condition. Polycystic kidney disease, which is largely unheardent, is less common and is often lethal early in life.
Congenital hepatic fibrosis is a disease of the liver that is present from birth. The hepatic portal system's congenital hepatic fibrosis is characterized by the inability of the bile ducts and the blood vessels. Bile ducts in Bile ducts transport bile from the liver to gallbladder and a small intestine. The hepatic portal network system is a branching network of veins that carry blood from the digestive tract to the liver for processing. In the hepatic portal system, the portal veins become constricted due to excessive blood pressure and portal tract fibrosis results in elevated blood pressure. An enlarged liver and spleen are common among people with congenital hepatic fibrosis. People affected by the disease, hard deposits in the gallbladder or bile ducts, or gallbladder cancer are also vulnerable to liver or gallbladder cancer. Congenital hepatic fibrosis may occur alone or in the case of isolated congenital hepatic fibrosis, see the figure.
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