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PCB - PubMed

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Last Updated: 08 September 2022

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A review of the mechanisms of by-product PCB formation in pigments, dyes and paints.

The bulk of existing research has solely concentrated on detecting the presence of the key PCBs in various products, with a particular focus on the most PCB congeners, PCB11, and PCB209. PCB profiles in paints and pigments can be just as detailed as industrial chemical mixtures. The presence of 149 unique PCBs in paint samples was discovered during this analysis. Just 141 unique PCBs have been documented in all five of the main commercial Aroclor formulations, for comparison. In azo pigments, total PCB levels in those paint samples can be high, with concentrations as high as 919 mg kg-1 reported. We've assembled congener profiles from 140 different samples from the open scientific literature in this paper, which we've published in the supplementary material as a useful resource for others to use in source identification applications.

Source link: https://doi.org/10.1016/j.scitotenv.2022.158529


Metabolism of 3-Chlorobiphenyl (PCB 2) in a Human-Relevant Cell Line: Evidence of Dechlorinated Metabolites.

In the cell culture media from HepG2 cells exposed for 24 h to ten nM PCB 2 metabolites belonging to 13 metabolite classes, five dechlorinated metabolite classes, including five metabolite classes, were identified in the cell culture media from HepG2 cells exposed for 24 h to ten nM PCB 2 or 3. 6 nM PCB 2. The PCB 2 metabolite profiles differed from those obtained in samples from a previous study with PCB 11 under identical experimental conditions. In human liver microsomal incubations with monohydroxylated PCB 2 metabolites, but not PCB 2, a dechlorinated dihydroxylated metabolite was also present in human liver microsomal incubations with monohydroxylated PCB 2 metabolites but not PCB 2.

Source link: https://doi.org/10.1021/acs.est.2c03687


Vermiremediation applied to PCB and PCDD/F contaminated soils and its implications for percolating water.

PCDD/Fs and PCBs are ubiquitous persistent pollutants with reduced bioavailability, which bioremediation using soil fauna is still underway to handle. This study sought to investigate earthworms' decontamination of PCDD/F and PCB polluted soils in Brescia-Caffaro, solely and with plants; simulate earthworms' activities in groundwater contamination process and nutrient mobility; E. fetida soil; contaminated soil with E. fetida; polluted soil with E. fetida; contaminated soil with E. fetida; contaminated soil with E. fetida; and lecontaminated soil with L. sativum; E. fetida contaminated soil; and L. sativum soil; contaminated soil with E. fetida; and L. sativum contaminated soil contaminated soil; Treatments did not differ in total PCBs concentration, but CEfLs congeners concentrations were less threatening; CEf and CLs resulted in lower PCDD/Fs levels. Earthworms may cause increased contaminants and soluble reactive phosphorous in percolating water.

Source link: https://doi.org/10.1016/j.envres.2022.113765


PCB exposure is associated with reduction of endosymbionts in riparian spider microbiomes.

Microbial populations, including endosymbionts, play a variety of roles in host biology and reproduction, but contamination can result in an imbalance in the microbiome composition, with subsequent impacts on host health. Whole spider DNA from sites with either low or high PCB contamination was extracted, and spider microbiota was determined by partial 16S RNA gene amplicon sequencing. The high PCB's site was 63 percent and 98 percent lower for tetragnathids and araneids, respectively, than at the low PCB's low PCB site.

Source link: https://doi.org/10.1016/j.scitotenv.2022.156726


Nrf2a dependent and independent effects of early life exposure to 3,3'-dichlorobiphenyl (PCB-11) in zebrafish (Danio rerio).

Prior studies in zebrafish have revealed that 0. 2 bcM exposures to 4-PCB-11-Sulfate after 1 day of fertilization, beginning at 1 day post fertilization, promoted hepatic neutral lipid accumulation in larvae at 15 dpf. Exposures ranged from 1-15 dpf to either 0. 05 percent DMSO or DMSO-matched 0. 2 % u00b5M 4-PCB-11-Sulfate, and 15 dpf subsets of larvae were imaged for overall morphology, primary pancreatic islet region, and RNAseq sampling. At 15 dpf, unbiased of genotype, fish exposed to 4-PCB-11-Sulfate survived by an average of 88% in comparison to unexposed fish, who survived 65-73%, with primary pancreatic islets 8 percent larger than unexposed fish. Fish growth at 15 dpf was dependent on genotype, with Nrf2a mutant fish a substantial 3-5% shorter than wildtype fish, and an interaction effect was observed where Nrf2a mutant fish exposed to 4-PCB-11-Sulfate saw a significant decline in the omega-3 fatty acid DHA compared to unexposed mutant fish.

Source link: https://doi.org/10.1016/j.aquatox.2022.106219


Combined read- and assembly-based metagenomics to reconstruct a Dehalococcoides mccartyi genome from PCB-contaminated sediments and evaluate functional differences among organohalide-respiring consortia in the presence of different halogenated contaminants.

Dehalococcoides sp. : Microbial communities that support the respiration of halogenated organic pollutants by Microbial communities that support the deposition of halogenated organic contaminants. However, it is also unknown if Dehalococcoides-containing microbial communities present in sediment-free environments quantitatively match those of sediment environments. pcbA1 and pcbA4/5-like rdhA were missing, according to phylogenetic analysis of reductive dehalogenase gene sequences within the MAG, although several candidate PCB dehalogenase genes and possibly novel rdhA sequences were reported, although several candidate rdhA and pcbA4/5-like rdhA were missing, while several candidate PCB dehalogene rdhA4/5-like rdhA1 and rdhA4/5-based on rdhA1 and rdhA1 and potentially novel rdhA4/5-based rdhA4/5-like ase gene sequences and possibly novel rdhA4/5-based on pcbA4/5-like rdhA.

Source link: https://doi.org/10.1093/femsec/fiac067

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions