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paraphrased embryo transfer in natural cycles of frozen thawed embryo transfer Objective We wanted to know whether elevated progesterone levels on the day before ovulation affected pregnancy outcomes. Patients were divided into two groups based on their progesterone levels the day before ovulation: the progesterone elevation group and the traditional progesterone group. Results Overall 1159 women with tubal factor infertility who underwent NC-FET were registered, including 666 women who received cleavage-stage embryo transfers and 493 women who received blastocyst embryo transfers. Following the transfer of two cleavage-stage embryos following the transfer of two embryos, we found that elevated progesterone levels raised the clinical pregnancy rate after correcting for various confounders, but did not influence the pregnancy rate when blastocyst-stage embryos were transferred. The dose of progesterone had no effect on the clinical pregnancy rate in patients undergoing blastocyst-stage NC-FET.
Source link: https://europepmc.org/article/MED/35901839
Background The development of a non-invasive diagnostic tool for multiple ovulation prediction has been able to increase the effectiveness of multiple ovulation prediction. In both groups at 1 st detection, the evaluation of reproductive hormones revealed that FSH, E2 and AMH levels were positively related to the embryo formation, while LH and P4 concentrations were negative in both groups. In the IE and SE groups, respectively, comparisons of high and low embryonic yield populations, 56 and 53 differing metabolites were identified in the IE and SE group. Conclusions This research found that FSH, P4, AMH, the PC-relevant metabolites, and several anomic acids, as well as some anomic acids, could be potential biomarkers for embryonic yield prediction in ovine multiple ovulation. The findings can help to clarify the relationship between blood samples and ovarian function as well as provide a theoretical basis for the multiple ovulation prediction.
Source link: https://europepmc.org/article/MED/35883090
The primary outcome was the continuing pregnancy rate or live birth rate, according to the primary outcome measure. Result The OPR/LBR climbed among letrozole FETs than among programmed FETs but not comparable to natural FETs. In the natural FET group, the CLR was smaller than in the programmed FET group. There were no differences in CLRs between letrozole and programmed FETs, nor between letrozole and programmed FETs, and between letrozole and programmed FETs, as well as between letrozole and programmed FETs, as well as between letrozole and programmed FETs and letrozole and natural FETs. The OPR/LBR among letrozole FETs, among ovulatory women, was higher than those in programmed FETs. Both letrozole FETs and natural FETs were significantly lower than in programted FETs. The OPR/LBR in the letrozole FET group was similar to that in the programmed FET group, especially among anovulatory women. Conclusion Letrozole and natural FET clinical outcomes were improved compared to programmed FET findings.
Source link: https://europepmc.org/article/MED/35863997
Every menstrual cycle, many follicles, are beginning to develop, but only a limited number of ovulate. The physiological mechanism that controls ovulation number is unknown; a number of mathematical models can explain it; however, these models have no physiological evidence; it is unknown. We propose a physiological mechanism for ovulation number control here, which allows for the selection of a limited number of follicles out of many others, and then examine it in a mathematical model of follicular growth. This approach also explains how chronic hyperandrogenism disrupts ovulation in polycystic ovary syndrome, a common cause of fertility problems.
Source link: https://europepmc.org/article/MED/35909517
In the treatment of inability to have children crops patients with endocrine, Aims To ask a lot of questions and try to find the truth about the drug-based success of letrozole and human malegonadotropin. Materials and methods An total of 160 children crops patients with endocrine problems that are not typical for those in our hospital from March 2019 to March 2022 were chosen as the subjects of this investigation into how things were in the past study and were divided into instances of observation, making a determination group determine whether or not the control group was treated with human menopausal gonadotropin. Letrozole can help increase sex hormone levels in pregnant women.
Source link: https://europepmc.org/article/MED/35860181
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