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Osteophyte - Springer Nature

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Last Updated: 23 September 2022

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Osteophytes mediate the associations between cartilage morphology and changes in knee symptoms in patients with knee osteoarthritis

Aims To see if osteophytes could link cartilage defects and cartilage volume with knee pain change. Methods: The Vitamin D Effects on Osteoarthritis study's participants were analyzed as a cohort. At baseline and follow-up, the Western Ontario and McMaster Universities Osteoarthritis Index was used to measure knee pains at baseline and follow-up. After adjustment for age, sex, body mass index, and intervention, cartilage defects were strongly associated with rise in total knee pain, change in weight-bearing pain, and decrease in non-weight-bearing pain. The association of cartilage defects with decline in total knee pain and increase in weight bearing pain and dysfunction were discussed by Lateal tibiofemoral and patellar osteophyte, as well as change in weight bearing pain and depression. Both cartilage defects and cartilage volume had no effect on knee pain changes.

Source link: https://doi.org/10.1186/s13075-022-02905-8

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions