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Oedema - Wiley Online Library

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Last Updated: 24 May 2022

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Proteomic analysis of vitreous humour of eyes with diabetic macular oedema: a systematic review

The pathophysiology of diabetic macular oedema remains unclear. On 19 September 2021, we systematically searched 13 literature databases to summarize the available information on protein changes in DME detected by MS. Two authors reviewed the studies for inclusion, extracted results, and assessed risk of bias independently. Eligible studies were defined as those that used samples from human eyes with DME analysed with MS. A total of 62 eyes from 60 patients were included in the study group, while 48 eyes from 48 patients were used as control group. When compared to controls, Proteomic results showed significant differences in the vitreous protein levels in patients with DME patients. Vitamin D-binding protein in DME has been found in three studies or more. Apolipoprotein AIII, apolipoprotein AIII, apolipoprotein AIII, apolipoprotein AII, apolipoprotein AIII, apolipoprotein AIV, apolipoprotein AIV, apolipoprotein AIII, apolipoprotein AIII, ad.

Source link: https://onlinelibrary.wiley.com/doi/10.1111/aos.15168

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions