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Neurotrophic Keratitis - PubMed

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Last Updated: 16 June 2022

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Neurotrophic Keratitis Due to Congenital Corneal Anesthesia with Deafness, Hypotonia, Intellectual Disability, Face Abnormality and Metabolic Disorder: A New Syndrome?

"We present a patient with multiple systemic and neurological disorders who presented to the ophthalmology department due to corneal erosion that was unresponsive to treatment in this case study. " Brain magnetic resonance imaging revealed bilateral trigeminal hypoplasia and the diagnosis of neurotrophic keratopathy as a result of bilateral congenital corneal anesthesia was made. The discrepancy between clinical signs and symptoms or treatment non-response in cases of corneal erosions should compel the ophthalmologists to suspect trigeminal dysfunction. MRI is the gold standard used to establish congenital corneal anesthesia and to distinguish from other potential neurotrophic keratitis causes. ".

Source link: https://doi.org/10.3390/medicina58050657


Neurotrophic Keratitis in a Pediatric Patient With Goldenhar Syndrome and Trigeminal Aplasia Successfully Treated by Corneal Neurotization.

"The authors review unusual occurrence of a 6-year-old boy with right-sided Goldenhar syndrome and trigeminal nerve aplasia who had neurotrophic keratopathy. " The patient underwent indirect corneal neurotization by a sural nerve autograft anastomosed to the contralateral supratrochlear nerve to prevent further corneal complications. The corneal anesthesia should be suspected in Goldenhar syndrome ophthalmologic abnormalities and followed until corneal changes become irreversible. Since corneal neurotization can effectively improve corneal sensation, it could be considered as a early therapeutic alternative to prevent refractory NK. ".

Source link: https://doi.org/10.1097/IOP.0000000000002086

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions