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"As the severe acute respiratory syndrome coronavirus 2 is spreading around the world, it became apparent that the SARS-CoV-2 virus infects multiple organs, including the brain. " Patients with COVID-19 infection suffer a variety of health problems, from headaches to life-threatening strokes, according to several scientific studies. Although the exact mechanism by which the SARS-CoV-2 virus affects the brain is not understood, many theories have been advanced, including direct and indirect routes induced by the virus. ".
Source link: https://europepmc.org/article/MED/34782556
"Tissue-resident memory T cells" are a subset of antigen-experienced T cells that are always retained in a given tissue with limited trafficking throughout the circulation. " T RM have been shown to be rapid and effective against tissue infection, and T RM density correlates with effective antitumor responses. Intriguingly, the number of CD8 T RM in patients with neuroinflammatory disorders such as multiple sclerosis or neurodegenerative disorders has risen in the central nervous system of patients with neuroinflammatory diseases such as multiple sclerosis or neurodegenerative diseases. In this article, we discuss current findings regarding the number of CNS-resident CD8 T cells and their role in CNS autoimmunity.
Source link: https://europepmc.org/article/MED/35644112
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