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Multiple Sclerosis - U.S. Department of Veterans Affairs

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Last Updated: 13 September 2022

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High Correlations Among Worldwide Prevalences of Dementias, Parkinson's Disease, Multiple Sclerosis, and Motor Neuron Diseases Indicate Common Causative Factors.

Although the etiology of these diseases is unclear, high correlation disease rates show the presence of common etiologic causes. P. 9, P. 9, We discovered that all six pairwise correlations among the four diseases' prevalences were extremely high>. 9, P. 9.

Source link: https://doi.org/10.1177/26331055221117598


Functional connectivity in the dorsal network of the cervical spinal cord is correlated with diffusion tensor imaging indices in relapsing-remitting multiple sclerosis.

Focal lesions can also influence functional connectivity of the ventral and dorsal pathways in people with relapsing-remitting multiple sclerosis. Functional MRI at 3T can be used to determine resting-state FC. In a group of 26 RRMS participants with elevated cervical lesion load, low mobility, and minimally impaired sensorimotor function, as well as healthy controls, tissue integrity and FC in the cervical spinal cord were determined by diffusion tensor imaging and resting-state fMRI. In the normal-appearing white matter in the RRMS group relative to controls, lower fractional anisotropy and enhanced radial diffusivity were observed. The average FC in ventral and dorsal networks was similar between groups. In the normal-appearing tissue, significant associations were found between higher FC in the dorsal sensory network and several DTI markers of pathology. Dorsal FC, a standard-appearing grey matter, was positively associated with axial diffusivity and mean diffusivity.

Source link: https://doi.org/10.1016/j.nicl.2022.103127

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions