Methylmalonic Acid - Europe PMC

Ni Nanoparticles Embedded Ti3C2Tx-MXene Nanoarchitectures for Electrochemical Sensing of Methylmalonic Acid.

Ti3C2Tx sheets were assembled as an interactive conductive substrate as well as a breathable layer to nickel nanoparticles, preventing their surface oxidation and aggregation. MX-Ni's conversion into an electrochemical sensor resulted in a robust cathodic reduction current against methylmalonic acid, a biomarker of vitamin B12 deficiency. Ni NPs synergism with conductive Ti3C2Tx-Mens improved signal integrity in wide detection ranges from 0. 001 to 0. 017 pM of MMA, with a detection sensitivity down to 0. 12 pM.

Source link: https://europepmc.org/article/MED/35448291

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