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Methylene Diphenyl Diisocyanate - Europe PMC

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Last Updated: 02 May 2022

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Emission of methylene diphenyl diisocyanate and methylene dianiline during use of cure-in-place methylene diphenyl diisocyanate-based consumer products.

The aim of this research was to collect valid isocyanate and amine emission data when using different methylene diisocyanate-based polyurethane consumer products. The polyurethane resin, one-component foam, and two specific two-component adhesives used in parquet flooring were among the polyurethane compounds used. For any of the applications in the breathing zone air, no methylene diamine concentrations were above the acceptable level of quantification were found. These results showed that inhalation exposure to MDA or MDI would be minimal in the case of do-it-yourself consumer products containing MDI.

Source link: https://europepmc.org/article/MED/35319330


Absorption, distribution, metabolism, and excretion of methylene diphenyl diisocyanate and toluene diisocyanate: Many similarities and few differences.

High production volume chemicals used for the manufacture of polyurethanes are ethylene diphenyl diisocyanate and toluene diisocyanate. For both chemicals, the most relevant adverse health effects from overexposure in the workplace are isocyanate-induced asthma, lung function decrement, and, to a lesser degree, skin reactions. Many papers over the past two decades have addressed MDI and TDI's reactivity in biological media and the related biochemistry, which has increased the knowledge of their biochemical and physiological behavior. Both TDI and MDI exhibit very similar patterns in terms of reactivity to biological macromolecules, absorption, metabolism, and excretion.

Source link: https://europepmc.org/article/MED/35301910

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions