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In today study, the expression accounts of host-derived miRNAs in the cecal content of two laying hen types; Hy-line Gray and Lohmann Pink, which have dissimilar H_2S manufacturing, were defined; and their effects on H_2S production by controling the expression of intestine microbiota-associated genes were shown. The outcomes additionally revealed the presence of miRNA exosomes in the cecal content of laying chickens, and an analysis of possible miRNA-target connections between 9 differentially shared miRNAs and 9 differentially expressed microbial genetics related to H_2S production determined two methionine synthase genetics, Odosp_3416 and BF9343_2953, that are targeted by gga-miR-222a. Final thought The findings of the present study disclose both a physiological function whereby miRNAs form the cecal microbiota of laying hens and an approach to use host miRNAs to manipulate the microbiome and actively reveal vital microbial genetics to minimize H_2S discharges and reproduce eco-friendly laying hens.
Source link: https://doi.org/10.1186/s40168-021-01098-7
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