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Methionine Supplementation - Europe PMC

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Last Updated: 13 February 2022

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Beneficial impact of dietary methyl methionine sulfonium chloride and/or L-carnitine supplementation on growth performance, feed efficiency, and serum biochemical parameters in broiler chicken: role of IGF-1 and MSTN genes.

The aim of this research was to determine the effects of dietary supplementation with methyl methionium chloride and L-carnitine alone or in combination on broilers' growth by investigating the presence of IGF-1 and MSTN genes associated with growth in broilers. Female Ross 308 broiler chicks were divided into four groups, each of whom received a broiler starter diet and water daily ad libitum. Group 2 received 0. 25 g L-carnitine per liter of drinking water, group 3 received 0. 25 g MMSC per liter of drinking water, and group 4 received 0. 25 g L-carnitine and MMSC per liter of drinking water, while Group 3 received 0. 25 g L-carnitine per liter of drinking water, and group 4 received 0. 25 g L-carnitine per liter of drinking water, while group 4 received 0. 25 g L-carnitine per liters of L-carnitine per g L-carnitine per liter of L-carnitine per MMSC per liter of L-carnitine per liter of L-carnitine per liter of L-carnitine per liter of MMSC per liter of L-carnitine per liter of L-carnitine per liter of L-carnitine per liter of L-carnitine per liter of drinking water. We conclude that MMSC supplementation enhanced growth prospects by the upregulation of IGF-1 mRNA expression and downregulation of MSTN mRNA expression.

Source link: https://europepmc.org/article/MED/35141787


Insulin signaling and antioxidant proteins in adipose tissue explants from dairy cows challenged with hydrogen peroxide are altered by supplementation of arginine or arginine plus methionine.

Antiinflammatory and antioxidant responses in animals can be triggered by arginine and methionine. Like Met, it is unknown if Arg's supply of Arg will have a bearing on basic aspects of adipose tissue function in dairy cows, but it is unknown if it would have an effect on key aspects of adipose tissue function. In this experiment, subcutaneous AT was extracted from 4 lactating multiparous Holstein cows and used for incubations with the following: H2O2 plus greater Arg and methionine supply - or H2O2+ greater Arg and methionine supply - or a combination of both H2O2 and methionine production. In explants incubated with HPARG and HPARGMET, there were increasing numbers of solute carrier family 2 member 4 and HPARGMET, accompanied by an increase in the number of solute carrier family 2 member 4. Arg or Arg plus Met were neither influencing the mRNA abundance of genes associated with Arg metabolism, which was unrelated to Arg or Arg plus Met. The investigation of Arg supply with or without Met on adipose tissue function needs to be investigated by more systematic studies to determine the effect of adipose tissue function.

Source link: https://europepmc.org/article/MED/35137127


Folate supplementation during oocyte maturation positively impacts the folate-methionine metabolism in pre-implantation embryos.

The present research investigated the effect of external folic acid supplementation on oocyte maturation, blastocyst formation, and the expression of folate transporters, as well as folate metabolism enzymes in goat oocytes and pre-implantation embryos, although goat folates contain endogenous pool folates for growth. Cumulus cell expansion markers in cumulus cells were highly affected after 50 mM folic acid supplementation, indicating a higher degree of maturation.

Source link: https://europepmc.org/article/MED/35123312


Individualized Folic Acid Supplementation based on Polymorphisms of Methylenetetrahydrofolate Reductase (MTHFR) and Methionine Synthase Reductase (MTRR), Compared with Traditional Folic Acid Supplementation, Reduces Gestational Diabetes Mellitus

Methods: MTHFR C677T, A1298C, and MTRR A66G polymorphisms in 968 pregnant women were determined by genotype and allele frequencies. At four different ages, FA metabolism was ranked at four levels, and then pregnant women of various stages were supplemented with different doses of FA at different times. In the same hospital, the case group was monitored for pregnancy issues and compares with 1,940 pregnant women traditionally supplemented with FA in the same hospital. The incidence of GDM in the case group was significantly lower than that of the control group, especially in high-risk pregnant women after FA supplementation. Traditional FA supplementation based on personal behavior is contentious, but the use of polymorphisms of genes to define the FA metabolism of pregnant women can help reduce gestational diabetes, especially among high-risk pregnant women.

Source link: https://europepmc.org/article/PPR/PPR438640


Effects of Dietary Supplementation with 2-Hydroxy-4-(methylthio)-butanoic Acid Isopropyl Ester as a Methionine Supplement on Nitrogen Utilization in Steers.

The aim of the experiment was to investigate the effects of diet supplementation with 2-hydroxy-4-hydroxyl ester isopropyl ester on beef steers' nitrogen metabolism. Increasing the uric acid N/urinary N ratio in steers was consistent with increasing the urnary N/urinary N ratio, decreasing the nit retention and retention rate, as well as the fecal N/urinary N ratio. The steers used in the experiment were in the fattening period, which may account for HMB's nonsignificant effect on increasing the N utilization in steers. In further studies, it is recommended to investigate the consequences of the dietary addition of HMBi to growing cattle.

Source link: https://europepmc.org/article/MED/34828038

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions