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Background: Methicillin-resistant Staphylococcus aureus has been a deadly disease in healthcare clinics since the 1960s, but MRSA epidemiology has shifted since 1990, with new genetically distinct strains circulating among newly healthy people outside of healthcare settings. MRSA strains that are primarily skin and soft tissue infections, but they can also cause life-threatening invasive infections. CA-MRSA transmission to others can be largely due to skin-to-skin contact. Skin infections have been largely concentrated in limited public health education. Methods: To reduce CA-MRSA transmissions, we created a fine-grained agent-based model for Chicago. We used a fine-grained agent-based model for Chicago to determine where to focus interventions to minimize CA-MRSA transmissions. The overwhelming majority of transmission events occurred in households, on average, the majority of transmission events occurred in households, and colonized rather than infected agents were the source of the vast majority of transmission events. Conclusions: The results indicate that current MRSA prevention strategies in the United States are not particularly effective in reducing the incidence of CA-MRSA infections.
Source link: https://www.osti.gov/biblio/1626581
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