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Metastatic Prostate Cancer - U.S. Department of Veterans Affairs

Summarized by Plex Scholar
Last Updated: 27 January 2022

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Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease.

Amoeboid tumor cells produce symoglobin, RNA, caveolin-1, and the GTPase ADP-ribosylation factor 6, which are biologically active against tumor cells, endothelial cells, and fibroblasts, according to this article. In the circulation of several mouse models of prostate cancer, structures resembling large oncosomes were identified, and their prevalence was correlated with tumor formation. Migrating tumor cells also influence the tumor microenvironment and distant locations, thus accelerating advanced disease.

Source link: https://doi.org/10.1016/j.ajpath.2012.07.030

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions