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Metalloproteinase - ClinicalTrials.gov

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Last Updated: 11 March 2022

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Biochemical Efficacy of Cymbopogon Citratus Gel as Local Drug Delivery Agent in Reducing Matrix Metalloproteinase-8 Levels Intra-crevicularly in the Treatment of Stage II Periodontitis: A Randomized Controlled Clinical Trial

Since MMP-8 can be used as a predictive biomarker of treatment response, we're investigating clinically the safety of intra-pocket application of Cymbopogon citratus gel and biochemically on MMP-8 levels in gingival crevicular fluid of stage II periodontitis patients. Methods: A randomised controlled clinical trial was carried out on forty patients with stage II periodontitis divided equally into two groups. SRP provided Group-I with 2% lemongrass oil gel intra-pocket, and SRP was able to administer Group-I. Both groups were characterized before treatment and twelve weeks after. Periodontal pocket depth and clinical attachment loss were measured for both groups before and after surgery.

Source link: https://clinicaltrials.gov/ct2/show/NCT05241509

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions