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Metabolic Syndrome - ClinicalTrials.gov

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Last Updated: 23 June 2022

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A Novel Single Wave Assessment to Measure Cardiac Dysfunction and Metabolic Syndrome in Cancer Patients

To determine the degree of agreement between the single wave measurement of left ventricular ejection fraction in cancer patients and that obtained by routine 2-dimensional echocardiography, a single wave test was used to determine the degree of consistency.

Source link: https://clinicaltrials.gov/ct2/show/NCT04014231


Effect of Ellagic Acid Administration on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion

There aren't studies that show the safety of EA on Mets; patients take it without any prescription; nevertheless, it is important to determine the effect of the administration of EA on the components of metabolic syndrome, insulin tolerance, and insulin secretion. paraphrasedoutput:OBJECTIVES: The primary aim is to determine whether EA or placebo has an effect on metabolic syndrome proteins, insulin sensitivity, and insulin secretion.

Source link: https://clinicaltrials.gov/ct2/show/NCT04011618


Individualizing and Optimizing Nutrition to Prevent Metabolic Syndrome and To Improve Neurodevelopment in Preterm and Small for Gestational Age Infants

Hypotheses: Hypothesis 1: Hypotheses: Hypothesis number: In preterm infants, personalized and optimized diet could aid growth from birth to 36 weeks of postmenstrual age or discharge in comparison to standardized diet. Patients will be randomly assigned to either: Control: optimized diet: Patients will be randomized to either: Control: The patient will be randomized to either: Optimization: optimized diet: Milk fortification will be based on current recommendations and optimized by diet adjustment once a week based on blood samples of urea nitrogen and albumin, as well as rate of growth. The fortification of milk will be modified based on daily measurements of macronutrients in human milk using near-infrared technology.

Source link: https://clinicaltrials.gov/ct2/show/NCT02372136


Nursing Intervention in Two Risk Factors of the Metabolic Syndrome, Abdominal Obesity and Arterial Hypertension, and Quality of Life in the Climacteric Period

In addition, the life expectancy of women around has increased dramatically, and women live a third or more of their lives after the climacteric period with some risk factor. According to analysis done in various countries around the world, Metabolic Syndrome is present in 60% of the female population and rises in menopause. According to NCEP/ATPIII guidelines, a high prevalence of Metabolic Syndrome in pre- and postmenopausal women has been shown, with prevalence ranging from 26. 1 to 55%, with Ecuador and South Korea leading out in this last group. The rise in blood pressure in MS patients with insulin resistance is mainly due to insulin resistance; increased bioavailability of endothelial nitric oxide; and more activation of the Renin-Angiotensin-Aldosterone Device and the endothelin system; changes in the hormonal environment; and a decrease in the autonomic nervous system. In summary, estrogen deficiency can cause sympathetic hyperactivity and endothelial dysfunction by direct effect on the vessels as well as an age-related deleterious effect on the vascular endothelium. According to clinical and epidemiological studies, middle-aged women have at least one independent risk factor for chronic disease. It's clear how significant preventive work is, aimed at expanding, reducing, and eliminating the risk factors of the Metabolic Syndrome, which can impede women's overall wellbeing at this time. As arterial pressure for the diastolic and 90 mmHg has been reduced, efforts to keep it below 140 mmHg for the systolic and 90 mmHg were reduced by 2 to 3%, lowering cardiovascular risk by 2 to 3% for each mmHg. Primary health care plays a transcendent role in the regulation of risk factors, and in this context, prevention campaigns continue to emphasize behavioral changes, in which educational intervention, health advice, and the use of technologies have all been highly effective, contributing to the enhancement of the quality of life. 1. 3 Hypothesis 1: Hypothesis 1: Following the self-care nursing intervention, the clicial women in the experimental group's Climacteric women in the research study demonstrated two MS risk factors over those in the comparison group. Working hypothesis: Climacteric women in the experimental group have lower abdominal circumference after the self-care-based nursing intervention that was not in the comparison group. After the self-care-based nursing intervention in the experimental group, female participants in the experimental group have lower systolic blood pressures. Conceptual Hypothesis 2: Conceptual Hypothesis 2: After the self-care-based nursing intervention improved health-related quality of life in the experimental group relative to those in the comparison group, Climacteric women in the experimental group received a higher quality of life. After the self-care-based nursing intervention, Climacteric women in the experimental group's lowest scores in the urogenital measure fell slightly in the urogenital domain, according to those in the comparison group. Conceptual Hypothesis 3: Climacteric women in the experimental group after the self-care-based nursing intervention improved self-care services by increasing physical fitness in comparison to those in the comparison group. u2022 Climacteric women in the experimental group's improved physical fitness after the self-care-based nursing intervention, relative to those in the comparison group, with the same experimental group. 1. 4 GENERAL OBJECTIVE TO determine the effects of a Nursing Intervention based on self-care aimed at enhancing the monitoring of two Metabolic Syndrome risk factors and health-related quality of life in climactic women. The effect of the independent variable on the dependent variables will be determined. Two Type C Health Centers in San Antonio include Pichincha Health Center and Comite del Pueblo Health Centers. The aim of carrying out the report in these Centers is due to the fact that they have similar populations, and because the promotion of the health, prevention of diseases, and wellness of the people by cycles of life are included within the responsibilities of Health type C centers is based on the promotion of the wellness, prevention of illnesses, and prevention of cycling of life is within the scope of Country, including services of general medicine, gynecology, infirmary, maternity, and emergency among the services of short stay and emergency, It is worth noting that the health center's hypertensive programmers meet three times a month and carry out programs aimed at health promotion and disease prevention. In the case, the Intervention Phase involves intervention Design Phase Construction of the mobile app and content of the intervention Phase It will be tested and developed as a result of the investigation of content that would be used for the intervention of the mobile phone between the months of April and July 2021, which will support the nursing counseling style included in the intervention. Finally, health care professionals with long experience in dealing with women in the climactic stage and women with Metabolic Syndrome's presence will be consulted. Once the required content modifications and feedback from the participants who will be included in the research phase have been obtained, the first iteration phase of the low-fidelity software prototype will be built, which will include the paper prototype, menu page, and screens that will display the first intervention module and content. They will test and give feedback on the prototype in the first meeting with the participants to ensure the logical creation meets the participants's needs, then the researcher will consult with health experts to socialize the module's content and provide feedback. Subsequently, the high-fidelity prototype will be built with the actual software home page, menu page, and modules for the intervention to ensure usability, and user feedback will be used to test the prototype, refine, tweak, and test its usability. Not to mention lowering the cost of traveling to health centers, users will use the app to enhance face-to-face individual counseling, virtual group education, and virtual physical fitness by providing remote nursing services from primary care to the home. According to what has previously stated, a first meeting with the physical fitness instructor will be held to socialize the physical fitness curriculum and the tool to be used during the participant's testing and subsequent diagnosis of their physical health during the month of July. These students will not be aware of the organisation to which the participants belong a week after the initial meeting was requested collaboration of students of physical culture of the 8th semester. In the month of August, the researcher will conduct a second face-to-face meeting with the nursing interns to whom the researcher will instruct in the use of the instruments in the pre- and post-test, as well as in the analysis of anthropometric parameters and vital signs. Execution of the Intervention In the first instance, the participants of the group comparison who participate in the Center of Health of the People and those that are registered in the Program of Hypertension will be given regular attention by the Institution on group discussions, health fairs based on general problems of the illness, and group sessions twice a week. On the other hand, the participants of the experimental group will receive support through: Educational assistance with technological assistance, educational sessions, and physical fitness sessions three times a week physically and a single walking session.

Source link: https://clinicaltrials.gov/ct2/show/NCT05387174


A Randomized Phase 3 Trial of Metformin in Patients Initiating Androgen Deprivation Therapy as Prevention and Intervention of Metabolic Syndrome: The Prime Study

After 18 months of research, the primary aim of this research will determine if there are differences between arms in terms of the proportion of participants who meet the diagnostic criteria for metabolic syndrome. According to statistics, one in every seven Canadian men will be diagnosed with prostate cancer in their lifetime. The burden of ADT toxico in prostate cancer survivors remains high and increasing as ADT is now used alone or in combination with other drugs in virtually every man with advanced prostate cancer for longer stretches of time. The investigators predict that the addition of metformin to a program of ADT will reduce the number of participants with metabolic syndrome at 18 months after the introduction of ADT and may minimize the occurrence of specific aspects of metabolic syndrome in men with advanced prostate cancer.

Source link: https://clinicaltrials.gov/ct2/show/NCT03031821


Effect of a Synbiotic on Body Fat Mass, Weight Management, Traits of Metabolic Syndrome and Gut Permeability in Individuals With Abdominal Overweight: a Randomised, Controlled, Double-blind Clinical Study

Since acacia gum was shown to raise the number of lactobacilli in the gut and, therefore, their propagation and, consequently, their effects, the combination of these Lactobacillus strains with acacia gum is expected to produce even more pronounced outcomes. After obtaining confirmative evidence, the target parameters were chosen for allowing a health claim under the Health Claim Directive of the EU and/or the REGULATION No 609/2013 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL's No 609/2013 for Food for Special Medical Purposes. Beneficial effect on long-term glycemia, obesity control, waist circumference, or body fat mass as determined by HbA1c improves weight control, while lowering insulin resistance, a risk factor for type 2 diabetes, has been found by HOMA-IR, which is a risk factor for coronary heart disease. It is notable that EFSA has admitted the involvement of type 2 diabetes in health conditions on these target parameters despite the fact that these parameters are similar from healthy to impaired metabolism. Body fat in people with type 2 diabetes was the target parameter with the lowest estimated sample size, taking this into account.

Source link: https://clinicaltrials.gov/ct2/show/NCT05405205


Randomised, Controlled, Double-blind Clinical Study on the Effect of a Synbiotic on Body Fat Mass, Weight Management, Metabolic Syndrome and Other Risk Factors for CVD and Diabetes, on Fecal Microbiota and Adverse Effects

Since acacia gum was shown to raise the number of lactobacilli in the gut and, therefore, their propagation and, hence their effects, they are expected to have even more pronounceable outcomes. The dosage of 10 g/day acacia gum was shown to be sufficient for producing fecal lactobacilli and bifidobacterial growth.

Source link: https://clinicaltrials.gov/ct2/show/NCT04754464

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions